杜氏肌营养不良症与 1 型强直性肌营养不良症的吞咽困难。
Dysphagia in Duchenne muscular dystrophy versus myotonic dystrophy type 1.
机构信息
Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Fukuoka University, 7-45-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan.
出版信息
Muscle Nerve. 2012 Oct;46(4):490-5. doi: 10.1002/mus.23364.
INTRODUCTION
In this study we aimed to demonstrate the distinctive features of dysphagia in patients with myotonic dystrophy type 1 (DM1) and Duchenne muscular dystrophy (DMD).
METHODS
Diet-type score (DTS) and maximum tongue pressure (MTP) were measured in 20 DM1 and 24 DMD patients; all patients were also examined by videofluoroscopy (VF). We used VF to measure the range of hyoid bone excursion (RHBE) during pharyngeal transit time and the area of pharyngeal residue (APR) after the first swallow.
RESULTS
RHBE and APR values for DM1 patients were significantly greater than those for DMD patients. DTS and MTP did not differ between patients. A significant correlation was observed between DTS, MTP, and RHBE in DMD patients, but not in DM1 patients.
CONCLUSIONS
Our findings reveal the differences in the distinctive features of dysphagia in DM1 and DMD. Adjustments in the diet of DMD patients in accordance with swallowing ability could be useful.
简介
本研究旨在展示 1 型肌强直性营养不良（DM1）和杜氏肌营养不良（DMD）患者吞咽困难的特征。
方法
对 20 例 DM1 患者和 24 例 DMD 患者进行饮食类型评分（DTS）和最大舌压（MTP）测量；所有患者均行吞咽造影检查（VF）。我们使用 VF 测量咽通过时间时舌骨上移范围（RHBE）和第一次吞咽后咽残留面积（APR）。
结果
DM1 患者的 RHBE 和 APR 值明显大于 DMD 患者。DTS 和 MTP 两组患者之间无差异。DMD 患者的 DTS、MTP 与 RHBE 之间存在显著相关性，而 DM1 患者无相关性。
结论
本研究结果揭示了 DM1 和 DMD 吞咽困难特征的差异。根据吞咽能力调整 DMD 患者的饮食可能是有用的。
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