State Key Laboratory of Virology, College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, People's Republic of China.
Luminescence. 2013 Jul-Aug;28(4):602-6. doi: 10.1002/bio.2406. Epub 2012 Sep 17.
Two novel chemosensors (2a and 2b) were synthesized by facile condensation of the binding unit (L-histidine) and the fluorophores (anthracene and dansyl groups). Both of them displayed high selectivity and sensitivity towards Fe(3+) over other metal ions in aqueous solution. The sensing mechanism was based on the paramagnetic property of Fe(3+) that would lead to fluorescence quenching of the fluorophores when Fe(3+) was bound to the recognition units. The results showed that l-histidine was a good coordination motif for Fe(3+) and both the anthracene and dansyl groups can sensitively report the sensing information.
两种新型化学传感器（2a 和 2b）通过结合单元（L-组氨酸）和荧光团（蒽和丹磺酰基）的简便缩合合成。它们都在水溶液中对 Fe(3+)表现出高选择性和灵敏度，而对其他金属离子则没有。传感机制基于 Fe(3+)的顺磁性，当 Fe(3+)与识别单元结合时，会导致荧光团的荧光猝灭。结果表明，L-组氨酸是 Fe(3+)的良好配位基，蒽和丹磺酰基都可以敏感地报告传感信息。
