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2011年:坏血病奥德赛

2011: the scurvy Odyssey.

作者信息

Bernardino V R, Mendes-Bastos Pedro, Noronha Carla, Henriques Celia Coelho

机构信息

Department of Internal Medicine 2, Hospital Curry Cabral, Lisbon, Portugal.

出版信息

BMJ Case Rep. 2012 Sep 17;2012:bcr0220125819. doi: 10.1136/bcr-02-2012-5819.

DOI:10.1136/bcr-02-2012-5819
PMID:22987898
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4543164/
Abstract

The authors report the case of a 50-year-old alcoholic man with chronic hepatitis C virus infection, who presented to the emergency department with fever and exuberant ecchymoses and petechiae on both legs. After a careful examination and laboratory assessment, the not-so-obvious hypothesis of scurvy was disclosed. Simply with vitamin C replacement and nutritional advice, a dramatic improvement in his condition was observed. In modern societies, a generalised access to food renders scurvy as a rare disease, often misdiagnosed. A multidisciplinary approach is emphasised as the key to a more simple differential diagnosis, avoiding unnecessary exams and preventing serious complications, or even death, if left untreated.

摘要

作者报告了一例50岁慢性丙型肝炎病毒感染的酗酒男性病例,该患者因发热以及双下肢出现大量瘀斑和瘀点而就诊于急诊科。经过仔细检查和实验室评估,发现了不太明显的坏血病诊断。仅通过补充维生素C和给予营养建议,就观察到他的病情有了显著改善。在现代社会,由于普遍能够获取食物,坏血病已成为一种罕见疾病,常常被误诊。强调多学科方法是进行更简单鉴别诊断的关键,可避免不必要的检查,并防止严重并发症的发生,若不治疗甚至会导致死亡。

相似文献

1
2011: the scurvy Odyssey.2011年:坏血病奥德赛
BMJ Case Rep. 2012 Sep 17;2012:bcr0220125819. doi: 10.1136/bcr-02-2012-5819.
2
A rare presentation of an ancient disease: scurvy presenting as orthostatic hypotension.一种古老疾病的罕见表现:以体位性低血压为表现的坏血病。
BMJ Case Rep. 2014 May 23;2014:bcr2013201982. doi: 10.1136/bcr-2013-201982.
3
Lower limb ecchymosis in a man with a history of alcohol misuse.一名有酗酒史男性的下肢瘀斑
BMJ. 2021 Nov 4;375:n2511. doi: 10.1136/bmj.n2511.
4
[Scurvy presenting with ecchymotic purpura and hemorrhagic ulcers of the lower limbs].[以下肢瘀斑性紫癜和出血性溃疡为表现的坏血病]
Ann Dermatol Venereol. 2000 May;127(5):510-2.
5
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 39-1995. A 72-year-old man with exertional dyspnea, fatigue, and extensive ecchymoses and purpuric lesions.马萨诸塞州总医院病例记录。每周临床病理讨论。病例39 - 1995。一名72岁男性,有劳力性呼吸困难、疲劳以及广泛的瘀斑和紫癜性皮损。
N Engl J Med. 1995 Dec 21;333(25):1695-702. doi: 10.1056/NEJM199512213332508.
6
A case of vascular purpura with scurvy.一例伴有坏血病的血管性紫癜。
Recenti Prog Med. 1992 Nov;83(11):652-3.
7
Adult scurvy.成人坏血病
JAMA. 1985 Feb 8;253(6):805-7.
8
Gingival hypertrophy: a solitary manifestation of scurvy.牙龈肥大:坏血病的一种单独表现。
Am J Otolaryngol. 2008 Nov-Dec;29(6):426-8. doi: 10.1016/j.amjoto.2007.11.006. Epub 2008 Jun 16.
9
[Diffuse ecchymoses].
Rev Med Interne. 2016 Jun;37(6):437-8. doi: 10.1016/j.revmed.2015.09.007. Epub 2016 Mar 9.
10
Adult scurvy.成人坏血病
Ann Emerg Med. 1981 Dec;10(12):652-5. doi: 10.1016/s0196-0644(81)80092-3.

引用本文的文献

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Vitamin C Can Shorten the Length of Stay in the ICU: A Meta-Analysis.维生素 C 可缩短 ICU 住院时间:一项荟萃分析。
Nutrients. 2019 Mar 27;11(4):708. doi: 10.3390/nu11040708.
2
Vitamin C: the known and the unknown and Goldilocks.维生素C:已知、未知与恰到好处的状态
Oral Dis. 2016 Sep;22(6):463-93. doi: 10.1111/odi.12446. Epub 2016 Apr 14.

本文引用的文献

1
Scurvy in a man with schizophrenia.一名患有精神分裂症的男子患坏血病。
CMAJ. 2011 Aug 9;183(11):E760. doi: 10.1503/cmaj.080505. Epub 2011 May 9.
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Scurvy in a patient with AIDS: case report.艾滋病患者坏血病:病例报告。
Rev Soc Bras Med Trop. 2011 Jan-Feb;44(1):122-3. doi: 10.1590/s0037-86822011000100029.
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Inability to walk due to scurvy: A forgotten disease.因坏血病导致无法行走:一种被遗忘的疾病。
Ann Saudi Med. 2010 Jul-Aug;30(4):325-8. doi: 10.4103/0256-4947.65266.
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Scurvy is still present in developed countries.坏血病在发达国家仍然存在。
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MR imaging in a child with scurvy: a case report.一名患坏血病儿童的磁共振成像:病例报告
Korean J Radiol. 2007 Sep-Oct;8(5):443-7. doi: 10.3348/kjr.2007.8.5.443.
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Scurvy: a disease almost forgotten.坏血病:一种几乎被遗忘的疾病。
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Vitamin C deficiency and depletion in the United States: the Third National Health and Nutrition Examination Survey, 1988 to 1994.美国维生素C缺乏与耗竭情况:1988年至1994年第三次全国健康和营养检查调查
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Clinical usefulness of the oral ascorbic acid tolerance test in scurvy.口服抗坏血酸耐量试验在坏血病中的临床应用价值。
Am J Clin Nutr. 1959 Nov-Dec;7:630-3. doi: 10.1093/ajcn/7.6.630.
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Scurvy and anaemia.坏血病与贫血症。
Am J Med. 1962 Feb;32:240-50. doi: 10.1016/0002-9343(62)90293-0.
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The anaemia of adult scurvy.成人坏血病性贫血
Q J Med. 1953 Jul;22(87):309-29.