Vanderweckene P, Erpicum P, Krzesinski J-M
Université de Liège, Département de médecine, CHU Sart-Tilman, 4000 Liège, Belgique.
Rev Med Suisse. 2012 Aug 29;8(351):1604-10.
The interest of chronotherapy in the field of arterial hypertension is progressively rising, especially in treated hypertensive patients characterized by a small decrease of their blood pressure during the night, and therefore often presenting a high cardiovascular risk. There are more and more data showing that administration of one antihypertensive drug in the evening (and even aspirin) can improve the blood pressure control during the night and the day/night blood pressure pattern, and so can diminish the level of risk. The role of chronotherapy also emphasizes the interest of 24 h ambulatory blood pressure monitoring in the management of high risk hypertensive patients.
时间治疗学在动脉高血压领域的关注度正在逐步提高,尤其是在那些夜间血压仅有小幅下降的接受治疗的高血压患者中,因此这些患者常常具有较高的心血管风险。越来越多的数据表明,在晚上服用一种降压药物(甚至阿司匹林)可以改善夜间血压控制以及昼夜血压模式,从而降低风险水平。时间治疗学的作用还凸显了24小时动态血压监测在高危高血压患者管理中的重要性。