Dong Yu-Chao, Zhou Guo-Wu, Bai Chong, Huang Hai-Dong, Sun Qin-Ying, Huang Yi, Han Yi-Ping, Li Qiang
Department of Respirology, Changhai Hospital, Second Military Medical University, P.R. China.
Intern Med. 2012;51(18):2515-9. doi: 10.2169/internalmedicine.51.7672. Epub 2012 Sep 15.
Tracheobronchial foreign bodies (FBs) are frequently present in adults. This study reports our experience with the managements of FB and FB-related complications using flexible bronchoscopy.
We retrospectively reviewed the adult patients with FBs treated between 2001 and 2011 in China. The demographic and endoscopic data were collected and analyzed.
A total of 200 adult patients (136 men and 64 women) with an average age of 51 years were analyzed. The most common FBs included bones (51.0%), nut shells (15.0%), food boluses (7.0%), plastic toys or pen caps (6.5%). After FB aspiration occurred, only 11.0% were diagnosed within three days, while more than half of the patients (58.0%) delayed the diagnosis by more than one month. The incidence of FB-related complications was 79.5%, including granulation formation (76.5%), obstructive pneumonia (22.0%), hemorrhage (14.5%), atelectasis (10.0%) and endobronchial stenotic scarring (8.0%). In 96.5% of the patients, the FBs were successfully removed under flexible bronchoscopy. A total of 53 out of the 153 patients with granulation (34.6%) were managed by argon plasma coagulation (APC) or cryotherapy; two out of the sixteen patients with endobronchial stenotic scars were treated by balloon dilation under flexible bronchoscopy.
A high incidence of FB-related complications occurs, likely as a result of the long delay between aspiration and diagnosis, a proportion of which require endoscopic intervention. The removal of FBs under flexible bronchoscopy has a high success rate and therefore should be recommended for adults.
气管支气管异物(FBs)在成人中很常见。本研究报告了我们使用可弯曲支气管镜处理FBs及其相关并发症的经验。
我们回顾性分析了2001年至2011年在中国接受治疗的成年FBs患者。收集并分析了人口统计学和内镜数据。
共分析了200例成年患者(男性136例,女性64例),平均年龄51岁。最常见的FBs包括骨头(51.0%)、坚果壳(15.0%)、食物团块(7.0%)、塑料玩具或笔帽(6.5%)。异物吸入后,仅11.0%在三天内被诊断出来,而超过一半的患者(58.0%)诊断延迟超过一个月。FBs相关并发症的发生率为79.5%,包括肉芽组织形成(76.5%)、阻塞性肺炎(22.0%)、出血(14.5%)、肺不张(10.0%)和支气管内狭窄瘢痕形成(8.0%)。96.5%的患者在可弯曲支气管镜下成功取出异物。153例有肉芽组织的患者中有53例(34.6%)接受了氩等离子体凝固(APC)或冷冻治疗;16例有支气管内狭窄瘢痕的患者中有2例在可弯曲支气管镜下接受了球囊扩张治疗。
FBs相关并发症的发生率较高,可能是由于吸入与诊断之间的长时间延迟,其中一部分需要内镜干预。在可弯曲支气管镜下取出FBs成功率高,因此应推荐用于成人。