Kim Hyun-Soo, Sung Ji-Youn, Park Won Seo, Kim Youn Wha
Aerospace Medical Research Center, Aerospace Medical Center, Republic of Korea Air Force, Korea.
Intern Med. 2012;51(18):2555-8. doi: 10.2169/internalmedicine.51.8182. Epub 2012 Sep 15.
Gastrointestinal stromal tumors (GISTs) can present with focal calcification. However, the presence of extensive calcification that constitutes the major portion of a GIST is extremely rare and can be associated with diagnostic pitfalls. We herein present the first two cases of rare gastric GIST with predominantly calcified components that mimicked pancreatic solid and pseudopapillary neoplasms with extensive calcification. In patients presenting with hyper-dense, heavily calcified masses in the abdominal cavity, the possibility of GIST should be considered in the differential diagnosis. A careful search for cellular areas and the judicious application of immunostaining will thus make it possible to make a correct diagnosis.
胃肠道间质瘤（GISTs）可出现局灶性钙化。然而，广泛钙化构成GIST主要部分的情况极为罕见，且可能导致诊断陷阱。我们在此报告首例两例罕见的主要由钙化成分构成的胃GIST病例，其表现类似伴有广泛钙化的胰腺实性假乳头状肿瘤。对于腹腔内出现高密度、大量钙化肿块的患者，鉴别诊断时应考虑GIST的可能性。因此，仔细寻找细胞区域并合理应用免疫染色将有助于做出正确诊断。
