Kuru Satoshi, Tanahashi Tamotsu, Matsumoto Shinjirou, Kitamura Tetsuya, Konagaya Masaaki
Department of Neurology, Suzuka National Hospital.
Rinsho Shinkeigaku. 2012;52(9):685-7. doi: 10.5692/clinicalneurol.52.685.
We report a case of complete atrioventricular (AV) block in a 40-year-old patient with Duchenne muscular dystrophy (DMD). While he was bed-ridden and required mechanical ventilation, his cardiac involvement was mild. He had the deletion of exon 45-52 in the dystrophin gene. He underwent transient complete AV block and came to require pacemaker implantation due to recurrence of complete AV block ten days after the first attack. Electrophysiological study revealed mild prolonged AH and HV interval. Although DMD patients with AV block have been rarely reported so far, attention should be paid to AV block for patients who prolonged their lives.
我们报告了一例40岁的杜氏肌营养不良症（DMD）患者发生完全性房室传导阻滞的病例。当他卧床且需要机械通气时，其心脏受累情况较轻。他的肌营养不良蛋白基因存在外显子45 - 52缺失。他经历了短暂的完全性房室传导阻滞，并且在首次发作十天后因完全性房室传导阻滞复发而需要植入起搏器。电生理研究显示AH和HV间期轻度延长。尽管迄今为止很少有DMD患者发生房室传导阻滞的报道，但对于延长了生存期的患者，应关注房室传导阻滞。
