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评估成人脊柱畸形后路内固定融合术后症状性杆状骨折。

Assessment of symptomatic rod fracture after posterior instrumented fusion for adult spinal deformity.

机构信息

Department of Neurosurgery, University of Virginia, Health Sciences Center, Charlottesville, Virginia 22908, USA.

出版信息

Neurosurgery. 2012 Oct;71(4):862-7. doi: 10.1227/NEU.0b013e3182672aab.

Abstract

BACKGROUND

Improved understanding of rod fracture (RF) in adult spinal deformity could be valuable for implant design, surgical planning, and patient counseling.

OBJECTIVE

To evaluate symptomatic RF after posterior instrumented fusion for adult spinal deformity.

METHODS

A multicenter, retrospective review of RF in adult spinal deformity was performed. Inclusion criteria were spinal deformity, age older than 18 years, and more than 5 levels posterior instrumented fusion. Rod failures were divided into early (≤12 months) and late (>12 months).

RESULTS

Of 442 patients, 6.8% had symptomatic RF. RF rates were 8.6% for titanium alloy, 7.4% for stainless steel, and 2.7% for cobalt chromium. RF incidence after pedicle subtraction osteotomy (PSO) was 15.8%. Among patients with a PSO and RF, 89% had RF at or adjacent to the PSO. Mean time to early RF (63%) was 6.4 months (range, 2-12 months). Mean time to late RF (37%) was 31.8 months (range, 14-73 months). The majority of RFs after PSO (71%) were early (mean, 10 months). Among RF cases, mean sagittal vertical axis improved from preoperative (163 mm) to postoperative (76.9 mm) measures (P<.001); however, 16 had postoperative malalignment (sagittal vertical axis>50 mm; mean, 109 mm).

CONCLUSION

Symptomatic RF occurred in 6.8% of adult spinal deformity cases and in 15.8% of PSO patients. The rate of RF was lower with cobalt chromium than with titanium alloy or stainless steel. Early failure was most common after PSO and favored the PSO site, suggesting that RF may be caused by stress at the PSO site. Postoperative sagittal malalignment may increase the risk of RF.

摘要

背景

提高对成人脊柱畸形中杆断裂(RF)的理解对于植入物设计、手术规划和患者咨询可能具有重要意义。

目的

评估成人脊柱畸形后路融合术后的症状性 RF。

方法

对成人脊柱畸形中 RF 的多中心回顾性研究。纳入标准为脊柱畸形,年龄大于 18 岁,后路融合超过 5 个节段。将杆失效分为早期(≤12 个月)和晚期(>12 个月)。

结果

442 例患者中,6.8%有症状性 RF。钛合金、不锈钢和钴铬的 RF 发生率分别为 8.6%、7.4%和 2.7%。经椎弓根截骨术(PSO)后 RF 发生率为 15.8%。在 PSO 后出现 RF 的患者中,89%的 RF 发生在 PSO 处或其附近。早期 RF(63%)的平均时间为 6.4 个月(范围:2-12 个月)。晚期 RF(37%)的平均时间为 31.8 个月(范围:14-73 个月)。PSO 后(71%)的大多数 RF 为早期(平均 10 个月)。在 RF 病例中,矢状垂直轴从术前(163mm)到术后(76.9mm)的平均值改善(P<.001);然而,16 例术后出现失对线(矢状垂直轴>50mm;平均值为 109mm)。

结论

成人脊柱畸形病例中症状性 RF 发生率为 6.8%,PSO 患者中发生率为 15.8%。钴铬的 RF 发生率低于钛合金或不锈钢。PSO 后早期失效最为常见,且有利于 PSO 部位,提示 RF 可能是由于 PSO 部位的应力所致。术后矢状面失对线可能会增加 RF 的风险。

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