Department of Health Policy and Management, University of Pittsburgh Graduate School of Public Health, USA, and Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA (MR)
Institute for Health and Department of Economics, Rutgers University, New Brunswick, NJ, USA (LBR)
Med Decis Making. 2012 Sep-Oct;32(5):678-89. doi: 10.1177/0272989X12454941.
The appropriate development of a model begins with understanding the problem that is being represented. The aim of this article is to provide a series of consensus-based best practices regarding the process of model conceptualization. For the purpose of this series of papers, the authors consider the development of models whose purpose is to inform medical decisions and health-related resource allocation questions. They specifically divide the conceptualization process into two distinct components: the conceptualization of the problem, which converts knowledge of the health care process or decision into a representation of the problem, followed by the conceptualization of the model itself, which matches the attributes and characteristics of a particular modeling type to the needs of the problem being represented. Recommendations are made regarding the structure of the modeling team, agreement on the statement of the problem, the structure, perspective and target population of the model, and the interventions and outcomes represented. Best practices relating to the specific characteristics of model structure, and which characteristics of the problem might be most easily represented in a specific modeling method, are presented. Each section contains a number of recommendations that were iterated among the authors, as well as the wider modeling taskforce, jointly set up by the International Society for Pharmacoeconomics and Outcomes Research and the Society for Medical Decision Making.
模型的恰当开发始于对所代表问题的理解。本文旨在提供一系列基于共识的最佳实践，涉及模型概念化的过程。在本系列论文中，作者考虑开发旨在为医疗决策和与健康相关的资源分配问题提供信息的模型。他们特别将概念化过程分为两个不同的组件：问题的概念化，即将对医疗保健过程或决策的知识转化为问题的表示，然后是模型本身的概念化，即将特定建模类型的属性和特征与所代表问题的需求相匹配。就建模团队的结构、对问题的陈述、模型的结构、视角和目标人群以及所代表的干预措施和结果达成一致意见提出建议。介绍了与模型结构的具体特征以及特定建模方法最容易表示的问题特征有关的最佳实践。每个部分都包含一些建议，这些建议是在作者、国际药物经济学和结果研究学会以及医学决策学会共同设立的更广泛的建模工作组之间反复提出的。
