Quillan S, Malotte C K, Shlian D
University of California, Los Angeles.
J Am Coll Health. 1990 Jan;38(4):165-70. doi: 10.1080/07448481.1990.9938437.
In many parts of the world, tuberculosis (TB) is still a major cause of morbidity and mortality. Because of the high rate of worldwide TB infection, the University of California, Los Angeles (UCLA), requires nonimmigrant foreign students to have a tuberculin skin test before completing registration for classes. Out of 589 students tested, 57.6% were positive (n = 339) at the level of 5 mm induration or greater. All positive reactors with no contraindications to isoniazid (INH) were urged to take INH chemoprophylaxis (n = 290). Several strategies designed to improve compliance were used with all students. In addition, some students attended a lecture and discussion prior to initiation of therapy. Completion rates were low for all students, including those who attended the lecture-discussion session. Implications of the results for future screening activities are discussed.
在世界许多地区，结核病（TB）仍然是发病和死亡的主要原因。由于全球结核病感染率很高，加利福尼亚大学洛杉矶分校（UCLA）要求非移民外国学生在完成课程注册前进行结核菌素皮肤试验。在接受测试的589名学生中，硬结直径达到5毫米或更大时，57.6%呈阳性（n = 339）。所有对异烟肼（INH）无禁忌的阳性反应者都被敦促接受INH化学预防（n = 290）。针对所有学生采用了几种旨在提高依从性的策略。此外，一些学生在开始治疗前参加了讲座和讨论。所有学生的完成率都很低，包括参加讲座讨论环节的学生。文中讨论了这些结果对未来筛查活动的影响。
