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孕产妇并发症与低出生体重模式:高度近亲通婚女性中的相关风险因素

Pattern of Maternal Complications and Low Birth Weight: Associated Risk Factors among Highly Endogamous Women.

作者信息

Bener Abdulbari, Salameh Khalil M K, Yousafzai Mohammad T, Saleh Najah M

机构信息

Department of Epidemiology and Medical Statistices, Hamad General Hospital, Hamad Medical Corporation, Qatar ; Department Evidence for Population Health Unit, School of Epidemiology and Health Sciences, The University of Manchester, Manchester, UK ; Departments of Public Health and Medical Education, Weill Cornell Medical College, P.O. Box 3050, Doha, Qatar.

出版信息

ISRN Obstet Gynecol. 2012;2012:540495. doi: 10.5402/2012/540495. Epub 2012 Sep 8.

Abstract

Objective. The objective of the study was to examine the pattern of low birth weight LBW, maternal complications, and its related factors among Arab women in Qatar. Design. This is a prospective hospital-based study. Setting. The study was carried out in Women's Hospital, Doha. Subjects and Methods. Pregnant women in their third trimester were identified in the log book of Women's Hospital and recruited into the study during first week of January 2010 to July 2011. Only 1674 (out of 2238) Arab women (74.7%) consented to participate in this study. Data on clinical and biochemistry parameters were retrieved from medical records. Follow-up data on neonatal outcome was obtained from labor room register. Results. The incidence of LBW (<2500 g) was 6.7% among Arab women during 2010 in Qatar. Distribution of gestational diabetes mellitus (GDM), antepartum hemorrhage (APH), maternal anemia, premature rupture of membrane (PROM), maternal occupation, parity, sheesha smoking, and parental consanguinity were significantly different (P < 0.05) between mothers of LBW and normal birth weight NBW (≥2500 g) babies. Multivariable logistic regression analysis revealed that previous LBW, consanguinity, parity, smoking shesha, GDM, APH, anemia, PROM, maternal occupation, and housing condition were significantly associated with LBW adjusting for gestational age. Conclusion. Maternal complications such as GDM, APH, anemia, PROM, and smoking shesha during pregnancy are significantly increasing the risk of LBW outcome. Screening and prompt treatment for maternal complications and health education for smoking cessation during routine antenatal visits will help in substantial reduction of LBW outcome.

摘要

目的。本研究的目的是调查卡塔尔阿拉伯女性中低出生体重(LBW)、孕产妇并发症及其相关因素的模式。设计。这是一项基于医院的前瞻性研究。地点。研究在多哈的妇女医院进行。对象与方法。在妇女医院的日志中识别出孕晚期的孕妇,并于2010年1月的第一周至2011年7月招募入本研究。在2238名阿拉伯女性中,只有1674名(74.7%)同意参与本研究。从医疗记录中检索临床和生化参数的数据。从产房登记册中获取新生儿结局的随访数据。结果。2010年卡塔尔阿拉伯女性中低出生体重(<2500克)的发生率为6.7%。低出生体重儿(LBW)和正常出生体重儿(NBW,≥2500克)的母亲在妊娠糖尿病(GDM)、产前出血(APH)、孕产妇贫血、胎膜早破(PROM)、孕产妇职业、产次、水烟吸食和近亲结婚方面的分布存在显著差异(P<0.05)。多变量逻辑回归分析显示,在调整胎龄后,既往低出生体重、近亲结婚、产次、水烟吸食、GDM、APH、贫血、PROM、孕产妇职业和住房条件与低出生体重显著相关。结论。孕期的孕产妇并发症如GDM、APH、贫血、PROM和水烟吸食会显著增加低出生体重结局的风险。在常规产前检查中对孕产妇并发症进行筛查和及时治疗以及开展戒烟健康教育将有助于大幅降低低出生体重结局。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9932/3443983/1fa2514fd671/ISRN.OBGYN2012-540495.001.jpg

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