Bröker Mirelle E E, van Aalten Susanna M, Ijzermans Jan N M, Dwarkasing Roy S, Steegers Eric A P, de Man Robert A
Erasmus MC, Afd. Chirurgie, Rotterdam, the Netherlands.
Ned Tijdschr Geneeskd. 2012;156(38):A5102.
Hepatocellular adenomas are benign liver tumours which are mostly seen in young women. When women with such tumours attempt to become pregnant, they require special attention because of the risks of hormone-induced growth and spontaneous rupture of the tumour, which are caused by increased levels of steroid hormones during pregnancy. We present three patients with hepatocellular adenomas who were either pregnant or wished to become pregnant. These cases describe the complexity of the situation. The size of the hepatocellular adenoma increased during pregnancy in patient A and contrarily remained stable in patient B. Patient C was advised to not get pregnant before an intervention because of the tumour's central location within the liver. We also describe the general clinical presentation and treatment of patients with a hepatocellular adenoma.
肝细胞腺瘤是一种良性肝脏肿瘤，多见于年轻女性。患有此类肿瘤的女性在试图怀孕时，由于孕期类固醇激素水平升高会导致激素诱导的肿瘤生长和自发破裂风险，因此需要特别关注。我们介绍了三名患有肝细胞腺瘤的患者，她们要么已经怀孕，要么希望怀孕。这些病例描述了情况的复杂性。患者A的肝细胞腺瘤在孕期增大，而患者B的肿瘤则保持稳定。患者C因肿瘤位于肝脏中央位置，在干预治疗前被建议不要怀孕。我们还描述了肝细胞腺瘤患者的一般临床表现和治疗方法。
