Park Keuk Kyu, Won Yu Sam, Yang Jae Young, Choi Chun Sik, Han Ki Young
Department of Neurosurgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
J Korean Neurosurg Soc. 2012 Jul;52(1):52-4. doi: 10.3340/jkns.2012.52.1.52. Epub 2012 Jul 31.
A 10-year-old female patient presented with a rapidly growing nodular mass lesion on her right frontal area. On skull radiography and computed tomography (CT) imaging, this mass had a well-demarcated punch-out lesion with a transdiploic, exophytic soft tissue mass nodule on the frontal scalp. Magnetic resonance (MR) imaging revealed the presence of a 1.5×1.2×1 cm sized calvarial lesion. This lesion was hypointense on T1 and heterogenous hyperintense on T2 weighted MR images, and exhibited heterogeneous enhancement of the soft tissue filling the punch-out lesion after intravenous administration of gadolinium. En block removal of the tumor with resection of the rim of the normal bone was performed. The pathological diagnosis was intravascular papillary endothelial hyperplasia (IPEH). After surgery, no recurrence was found for 8 months. IPEH is a rare and benign reactive lesion usually found in thrombosed subcutaneous blood vessels. Involvement of skull bone is rare. In this article, we present a case of IPEH involving the calvarium, in a 10-year-old woman.
一名10岁女性患者，其右额部出现一个迅速增大的结节状肿块病变。在颅骨X线摄影和计算机断层扫描（CT）成像中，该肿块有一个边界清晰的穿凿样病变，额部头皮有一个经板障的、向外生长的软组织肿块结节。磁共振（MR）成像显示存在一个大小为1.5×1.2×1 cm的颅骨病变。该病变在T1加权MR图像上呈低信号，在T2加权MR图像上呈不均匀高信号，静脉注射钆后，填充穿凿样病变的软组织表现为不均匀强化。对肿瘤进行了整块切除，并切除了正常骨边缘。病理诊断为血管内乳头状内皮增生（IPEH）。术后8个月未发现复发。IPEH是一种罕见的良性反应性病变，通常见于血栓形成的皮下血管。累及颅骨者罕见。在本文中，我们报道了一例10岁女性累及颅骨的IPEH病例。
