Khrianin A A, Reshetnikov O V, Safronov I D, Trunov A N, Kulikova N B
Antibiot Khimioter. 2012;57(3-4):29-32.
Seventy five patients with urogenital chlamydial and mycoplasmic infections were enrolled in the trial. In the etiotropic therapy azithromycin was used in the standard dosage (1.0-1.5 g) depending on the infection. The treatment with azithromycin, in addition to the high eradication rates, was also evident of its effect on the cytokine levels in the patients, that was characteristic of a significant increase of the IFN-gamma level and a decrease of the IL-1beta and IL-6 levels in the blood.
75例泌尿生殖系统衣原体和支原体感染患者纳入该试验。在病因疗法中，根据感染情况使用标准剂量（1.0 - 1.5克）的阿奇霉素。阿奇霉素治疗除根除率高外，对患者细胞因子水平也有明显影响，其特征是血液中IFN-γ水平显著升高，IL-1β和IL-6水平降低。
