Li Xue-De, He Qing-Xin, Fan Sheng-Hai, Jiang Zhi-Yong, Wang Zhong-Xing
Department of Andrology, No. 181 Hospital of Chinese People's Liberation Army, Guilin, Guangxi 541002, China.
Zhonghua Nan Ke Xue. 2012 Jul;18(7):611-4.
To investigate the diagnosis and treatment of epididymal obstructive azoospermia (OA) by microsurgery.
We performed surgical scrotal exploration for 57 cases of OA whose obstruction was suspected to be in the epididymis. Those confirmed to be epididymal OA cases and with motile sperm in the epididymis underwent longitudinal-2-suture intussusceptive vasoepididymostomy (LIVES). And for those with sperm in the epididymal head only or with bilateral obstruction or absence of the vas deferens in the distal epididymis, the sperm were collected and subjected to cryopreservation for intracytoplasmic sperm injection (ICSI). After surgery, the patients were followed up for observation of the semen parameters and the rate of pregnancy.
Of the total number of patients, 53 (92.9%) were diagnosed with epididymal OA by scrotal exploration, 47 (82.5%) underwent microsurgery, and the other 10 (17.5%) received sperm cryopreservation. At 1 to 18 months after surgery, motile sperm were found in the ejaculate in 46.8% of the cases (22/47), natural pregnancy in 10.6% (5/47), and ICSI pregnancy in 18.5% (6/32).
With the development of microsurgery, non-invasive means should be the first choice for the diagnosis of OA. And surgical exploration can be employed to determine the location of obstruction and the option for treatment.
探讨显微外科手术治疗附睾梗阻性无精子症(OA)的诊断与治疗方法。
对57例怀疑附睾梗阻的OA患者进行阴囊探查手术。确诊为附睾OA且附睾中有活动精子的患者接受纵行二针法套叠式输精管附睾吻合术(LIVES)。对于仅附睾头部有精子或附睾远端双侧梗阻或输精管缺如的患者,收集精子并进行冷冻保存以备卵胞浆内单精子注射(ICSI)。术后对患者进行随访,观察精液参数和妊娠率。
经阴囊探查,53例(92.9%)患者被诊断为附睾OA,4