Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
High Alt Med Biol. 2012 Sep;13(3):185-92. doi: 10.1089/ham.2012.1008.
Recent studies have investigated visual analogue scales (VAS) as an alternative to the Lake Louise AMS Self-Report Score (LLS) for the self-assessment of acute mountain sickness (AMS). We investigated their use in adolescents.
The study was conducted during the 2009 and 2010 British Schools Exploring Society 35-day expeditions to Ladakh. Comparable ascent profiles were followed, reaching a maximum altitude of 6000 m. LLS and VAS AMS scores were recorded each morning. VAS comprised 100 mm lines for each LLS symptom; VAS scores were summed to give a composite daily total (VAS(c), expressed as a percentage). In 2010, an additional line was used to score overall "altitude sickness' (VAS(o)).
42 individuals participated in 2009 (83% compliance; mean age 17.4 years); 28 in 2010 (82% compliance; 17.5 years). 759 data points were recorded in 2009; 529 in 2010. There was a significant correlation between LLS and VAS(c) on both expeditions (rho=0.80, p<0.001 in 2009; rho=0.65, p<0.001 in 2010). These significant correlations remained when cases of AMS were analyzed separately. However, in all cases, the relationship between LLS and VAS was distorted, with a tendency for VAS to underscore symptoms of AMS when LLS<5. A VAS(c) value of 5.5% had an 82% specificity and sensitivity for all cases of AMS; VAS(c) of 9.5% had a 90% specificity and sensitivity for moderate and severe AMS.
Whilst adolescents are capable of self-monitoring for AMS using VAS, the relationship with LLS is distorted. The LLS, despite its limitations, therefore remains the preferred method for the self-assessment of AMS in adolescents.
最近的研究已经调查了视觉模拟量表（VAS）作为替代湖路易丝 AMS 自我报告评分（LLS）用于急性高山病（AMS）的自我评估。我们研究了它们在青少年中的使用。
该研究在 2009 年和 2010 年英国学校探索社会 35 天探险队到拉达克进行。遵循类似的上升曲线，达到最高海拔 6000 米。每天早上记录 LLS 和 VAS AMS 评分。VAS 为每个 LLS 症状包含 100 毫米的线; VAS 评分相加得到一个综合每日总分（VAS（c），表示为百分比）。在 2010 年，使用了另外一条线来评估总体“高空病”（VAS（o））。
2009 年有 42 人参加（83%的依从性;平均年龄 17.4 岁）; 2010 年有 28 人参加（82%的依从性; 17.5 岁）。2009 年记录了 759 个数据点; 2010 年记录了 529 个数据点。两次探险中，LLS 和 VAS（c）之间存在显著相关性（2009 年 rho=0.80，p<0.001; rho=0.65，p<0.001 在 2010 年）。当单独分析 AMS 病例时，这些显著相关性仍然存在。然而，在所有情况下，LLS 和 VAS 之间的关系都被扭曲了，当 LLS<5 时，VAS 倾向于强调 AMS 的症状。VAS（c）值为 5.5%时，所有 AMS 病例的特异性和敏感性为 82%; VAS（c）为 9.5%时，中度和重度 AMS 的特异性和敏感性为 90%。
尽管青少年能够使用 VAS 自我监测 AMS，但与 LLS 的关系被扭曲。尽管 LLS 存在局限性，但它仍然是青少年 AMS 自我评估的首选方法。
