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经导管主动脉瓣植入术与脑血管意外。

Transcatheter aortic valve implantation and cerebrovascular accidents.

机构信息

Department of Cardiology, Bern University Hospital, Bern, Switzerland.

出版信息

EuroIntervention. 2012 Sep;8 Suppl Q:Q60-9. doi: 10.4244/EIJV8SQA11.

Abstract

Transcatheter aortic valve implantation (TAVI) is an evidence-based treatment alternative for selected high-risk patients with symptomatic severe aortic stenosis as acknowledged in the most recent edition of the ESC Guidelines on Valvular Heart Disease 2012. However, periprocedural complications and in particular cerebrovascular accidents remain a matter of concern. While transcatheter heart valve technology continuously improves and the development of novel and even less invasive implantation techniques is on-going, cerebrovascular events complicating TAVI may abrogate the usual improvement in terms of prognosis and quality of life. This article describes the incidence of cerebrovascular events after cardiovascular procedures, provides an overview of the pathophysiological mechanisms as well as the impact on outcomes and provides some insights into preventive strategies as well as the acute management of these events.

摘要

经导管主动脉瓣植入术(TAVI)是一种基于证据的治疗选择,适用于有症状的高危重度主动脉瓣狭窄的选定患者,这在 2012 年 ESC 瓣膜性心脏病指南的最新版本中得到认可。然而,围手术期并发症,特别是脑血管意外,仍然是一个令人关注的问题。虽然经导管心脏瓣膜技术不断改进,新型甚至创伤更小的植入技术也在不断发展,但 TAVI 后并发的脑血管事件可能会使预后和生活质量的通常改善化为泡影。本文描述了心血管手术后脑血管事件的发生率,概述了病理生理机制及其对结局的影响,并对这些事件的预防策略和急性处理提供了一些见解。

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