University of Pennsylvania.
Blood. 2012 Sep 20;120(12):2355-7. doi: 10.1182/blood-2012-07-442756.
In this issue of Blood, Ye et al and Al Hawas et al clarify the roles of 2 key fusion proteins that regulate the agonist-stimulated release of bioactive factors from platelets, and thereby explain the defective hemostasis in patients with 2 rare genetic diseases.
在本期《Blood》中,叶等人和 Al Hawas 等人阐明了 2 种关键融合蛋白在调节血小板中生物活性因子的激动剂刺激释放中的作用,从而解释了 2 种罕见遗传性疾病患者存在的止血缺陷。