通过时空图像相关技术（STIC）测量胎儿心输出量和射血分数：男胎与女胎的比较
Fetal cardiac output and ejection fraction by spatio-temporal image correlation (STIC): comparison between male and female fetuses.
作者信息
Simioni Christiane, Araujo Júnior Edward, Martins Wellington P, Rolo Liliam Cristine, Rocha Luciane Alves da, Nardozza Luciano Marcondes Machado, Moron Antonio Fernandes
机构信息
Departamento de Obstetrícia, Universidade Federal de São Paulo, São Paulo, SP, Brasil.
出版信息
Rev Bras Cir Cardiovasc. 2012 Apr-Jun;27(2):275-82. doi: 10.5935/1678-9741.20120058.
OBJECTIVE
To compare the cardiac output (CO) and ejection fraction (EF) of the heart of male and female fetuses obtained by 3D-ultrasonography using spatio-temporal image correlation (STIC).
METHODS
We conducted a cross-sectional study with 216 normal fetuses, between 20 and 34 weeks of gestation, 108 male and 108 female. Ventricular volumes at the end of systole and diastole were obtained by STIC, and the volumetric assessments performed by the virtual organ computer-aided analysis (VOCAL) rotated 30º. To calculate the DC used the formula: DC = stroke volume / fetal heart rate, while for the FE used the formula: EF = stroke volume / end-diastolic volume. The DC (combined male and female) and EF (male and female) were compared using the unpaired t test and ANCOVA. Scatter plots were created with the percentiles 5, 50 and 95.
RESULTS
The average of DC combined, DC left, DC right, FE right and FE left, male and female were 240.07 mL/min, 122.67 mL/min, 123.40 mL/min, 72.84%, 67.22%, 270.56 mL/ min, 139.22 mL/min, 131.34 mL/min, 70.73% and 64.76% respectively, without statistical difference (P> 0.05).
CONCLUSIONS
The fetal CO and EF obtained by 3Dultrasonography (STIC) showed no significant difference in relation to gender.
目的
比较采用时空图像相关技术（STIC）的三维超声检查所获得的男性和女性胎儿心脏的心输出量（CO）和射血分数（EF）。
方法
我们对216例孕20至34周的正常胎儿进行了一项横断面研究，其中男性108例，女性108例。通过STIC获得收缩末期和舒张末期的心室容积，并采用虚拟器官计算机辅助分析（VOCAL）旋转30°进行容积评估。计算每搏输出量（DC）的公式为：DC = 每搏输出量 / 胎儿心率，而计算射血分数（FE）的公式为：EF = 每搏输出量 / 舒张末期容积。采用非配对t检验和协方差分析比较DC（合并男性和女性）和EF（男性和女性）。绘制第5、50和95百分位数的散点图。
结果
合并的DC、左心室DC、右心室DC、右心室FE和左心室FE的男性和女性平均值分别为240.07 mL/分钟、122.67 mL/分钟、123.40 mL/分钟、72.84%、67.22%、270.56 mL/分钟、139.22 mL/分钟、131.34 mL/分钟、70.73%和64.76%，无统计学差异（P > 0.05）。
结论
三维超声检查（STIC）所获得的胎儿CO和EF在性别方面无显著差异。
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