Amakhin D V, Veselkin N P
Tsitologiia. 2012;54(6):469-77.
Today it is well accepted that GABA can be co-localized and co-released with glycine in the same synapse. This article provides an overview of GABA and glycine co-localization and the effects of simultaneous activation of GABAA and glycine receptors. The review deals with mechanisms of direct and indirect receptor interaction, as well as with the effect of non-selective activation of glycine receptors by GABA.
如今,γ-氨基丁酸(GABA)可与甘氨酸在同一突触中共定位并共同释放这一观点已被广泛接受。本文概述了GABA与甘氨酸的共定位以及GABAA受体和甘氨酸受体同时激活的效应。该综述探讨了直接和间接受体相互作用的机制,以及GABA对甘氨酸受体非选择性激活的影响。