Yuzuncu Yıl University, Faculty of Science, Department of Analytical Chemistry, 65080 Van, Turkey.
Curr Drug Deliv. 2013 Feb;10(1):76-91. doi: 10.2174/1567201811310010014.
A number of Polycyclic Aromatic Hydrocarbons (PAHs) have been shown to be toxicants, and induce carcinogenic and immunotoxic effects. Since PAHs are often present in low concentrations and it may be difficult to determine them in complex matrices, it is therefore essential to use powerful analytical tools to separate and identify the analyses in the samples. In this paper, initially, a short description of the principles, instrumentation, and use of common extraction and analytical techniques for PAH pollutants and their metabolites will be made in light of the previously reported works and major reviews. Special attention will be given to the use of modern polarographic and voltammetric techniques on the mercury and different types of solid electrodes, together with their some practical applications. The main drawbacks and limitations of these methods will also be discussed.
许多多环芳烃（PAHs）已被证明是有毒物质，并会引起致癌和免疫毒性作用。由于 PAHs 通常存在于低浓度下，并且在复杂的基质中可能难以确定它们的存在，因此使用强大的分析工具来分离和识别样品中的分析物是至关重要的。在本文中，首先将根据以前的报告和主要综述，简要描述 PAH 污染物及其代谢物的常见提取和分析技术的原理、仪器和用途。特别关注现代极谱和伏安技术在汞和不同类型的固体电极上的应用，以及它们的一些实际应用。还将讨论这些方法的主要缺点和局限性。
