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澳大利亚儿童的血脂:值得关注吗?2005 - 2007年巴瑟尔顿健康研究。

Lipids in Australian children: cause for concern? 2005-2007 Busselton Health Study.

作者信息

Bell Lana, Davis Elizabeth, Knuiman Matthew, Divitini Mark, Beilby John, Hunter Michael, Hung Joseph

机构信息

Department of Endocrinology, Princess Margaret Hospital, Australia.

出版信息

J Paediatr Child Health. 2012 Oct;48(10):E172-7. doi: 10.1111/j.1440-1754.2012.02575.x. Epub 2012 Sep 23.

DOI:10.1111/j.1440-1754.2012.02575.x
PMID:22998088
Abstract

AIM

To report the current lipid status of Australian school children from a population-based sample and compare this to international and Australian data.

METHODS

A cross section of school children aged 6 to 16.9 years in Busselton, Western Australia (WA) between 2005 and 2007 had fasting lipids tested. The first analysis compares the Busselton sample to data recommended by the American Academy of Paediatrics (AAP) 2008. The second analysis compares the Busselton sample to data from the Schools Physical Activity and Nutrition Survey (SPANS) study, New South Wales (NSW), Australia, 2004 and the 1985 Australian Health and Fitness Survey (AHFS). The third analysis applies laboratory-reported cut-points in WA to report percentages over 'healthy desirable norms'.

RESULTS

Analysis 1: higher levels of total cholesterol and triglycerides in Busselton children compared to AAP data source. Boys had higher low-density lipoprotein (LDL) levels. Analysis 2: comparable rates of dyslipidaemia to SPANS 2004 but lower rates compared to the AHFS, 1985. Analysis 3: total and LDL-cholesterol above recommended range in 32.7% and 19.4% of boys and 38.2% and 24.6% of girls.

CONCLUSION

In a large population-based sample of Australian school children, we found a higher frequency of abnormal lipid profiles when compared to American data. In addition, many children have levels outside reported healthy norms for Australian children. Research tracking lipid profiles of Australian children into adulthood is needed to understand the association of these levels with future cardiovascular risk.

摘要

目的

报告来自基于人群样本的澳大利亚学童当前的血脂状况,并将其与国际和澳大利亚的数据进行比较。

方法

对2005年至2007年间西澳大利亚州(WA)巴瑟尔顿6至16.9岁的学童进行空腹血脂检测。首次分析将巴瑟尔顿样本与美国儿科学会(AAP)2008年推荐的数据进行比较。第二次分析将巴瑟尔顿样本与2004年新南威尔士州(NSW)澳大利亚学校体育活动与营养调查(SPANS)研究以及1985年澳大利亚健康与健身调查(AHFS)的数据进行比较。第三次分析应用西澳大利亚州实验室报告的切点来报告超过“健康理想标准”的百分比。

结果

分析1:与AAP数据源相比,巴瑟尔顿儿童的总胆固醇和甘油三酯水平更高。男孩的低密度脂蛋白(LDL)水平更高。分析2:血脂异常发生率与2004年的SPANS相当,但与1985年的AHFS相比更低。分析3:32.7%的男孩和38.2%的女孩的总胆固醇和LDL胆固醇高于推荐范围,19.4%的男孩和24.6%的女孩也是如此。

结论

在一个基于人群的大型澳大利亚学童样本中,我们发现与美国数据相比,血脂异常的发生率更高。此外,许多儿童的血脂水平超出了澳大利亚儿童报告的健康标准。需要对澳大利亚儿童的血脂状况进行追踪研究,直至成年,以了解这些血脂水平与未来心血管疾病风险之间的关联。

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