Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Immunity. 2012 Sep 21;37(3):447-9. doi: 10.1016/j.immuni.2012.09.006.
Obesity-induced inflammation contributes to multiple metabolic diseases. In this issue of Immunity, Lynch et al. (2012) show that invariant natural killer T (iNKT) cells are enriched in adipose tissue and induce anti-inflammatory pathways to confer protection against obesity.
肥胖引起的炎症会导致多种代谢疾病。在本期《免疫》中,Lynch 等人(2012)表明,不变自然杀伤 T(iNKT)细胞在脂肪组织中富集,并诱导抗炎途径,从而对肥胖起到保护作用。