Flodmark C E, Shen W, Punyanitya M, Leander P, Lanke J, Pietrobelli A
Childhood Obesity Unit, Childhood Centre Malmö, Skåne University Hospital, Malmö, Sweden.
Pediatr Obes. 2013 Apr;8(2):112-7. doi: 10.1111/j.2047-6310.2012.00095.x. Epub 2012 Sep 21.
Sagittal diameter (SAD) has been reported to correlate to visceral fat and cardiovascular risk factors. SAD is measured with the individual lying down, halfway between the lower rib margin and the iliac crest; it represents the mid-height of the abdomen. The aim of this study was to validate SAD measured using a recently-developed laser beam device (SAD(LDB) ) against SAD measured using MRI (SAD(MRI)).
Of 48 obese children (25 boys, 23 girls) aged 9-11 years on the waiting list for obesity treatment, 34 agreed to a baseline measurement, which was followed by repeated measurements 6 and 12 months later in 31 and 22 children respectively. MRI was used to examine SAD(MRI) at 5 cm above (SAD(MRI,cra) ) and below (SAD(MRI,cau)) the mid plane of the L4-5 intervertebral disc.
Each of the differences SAD(LBD) - SAD(MRI, cau) and SAD(LBD) - SAD(MRI,cra) was subjected to a repeated-measurements ANOVA; the visit did not have a statistically significant effect in either case (p = 0.19 and p = 0.72, respectively). The difference SAD(LBD) - SAD(MRI, cau) was 1.50 on average (p < 0.0001; CI 1.26-1.74) while the corresponding figure for SAD(LBD) -SAD(MRI, cra) was 1.26 (p < 0.0001; CI 1.04-1.49). Regression of the difference on the mean gave slopes of -0.09 (p = 0.25) and -0.04 (p = 0.57) respectively. Prediction of SAD(MRI) from SAD(LDB) can be performed in different ways: by means of linear regression or by means of an additive correction.
Thus, this laser device can be used instead of MRI to estimate SAD by using a simple correction.
矢状径(SAD)据报道与内脏脂肪及心血管危险因素相关。SAD是在个体仰卧位时,于下肋缘与髂嵴之间的中点测量;它代表腹部的中间高度。本研究的目的是验证使用最近开发的激光束装置测量的SAD(SAD(LDB))与使用磁共振成像(MRI)测量的SAD(SAD(MRI))的一致性。
在等待肥胖治疗的48名9至11岁肥胖儿童(25名男孩,23名女孩)中,34名同意进行基线测量,随后分别在6个月和12个月后对31名和22名儿童进行重复测量。使用MRI在L4 - 5椎间盘中间平面上方5厘米(SAD(MRI,cra))和下方5厘米(SAD(MRI,cau))处检查SAD(MRI)。
SAD(LBD) - SAD(MRI,cau)和SAD(LBD) - SAD(MRI,cra)的每一个差异均进行重复测量方差分析;在这两种情况下,随访均未产生统计学上的显著影响(分别为p = 0.19和p = 0.72)。SAD(LBD) - SAD(MRI,cau)的差异平均为1.50(p < 0.0001;CI 1.26 - 1.74),而SAD(LBD) - SAD(MRI,cra)的相应数值为1.26(p < 0.0001;CI 1.04 - 1.49)。差异对均值的回归分别给出斜率为 - 0.09(p = 0.25)和 - 0.04(p = 0.57)。可以通过不同方式从SAD(LDB)预测SAD(MRI):通过线性回归或通过加法校正。
因此,这种激光装置可通过简单校正替代MRI用于估计SAD。