Möller E, Olerup O
Institutionen för klinisk immunologi och Centrum för Bioteknik, Karolinska Institutet, Huddinge Sjukhus.
Nord Med. 1990;105(1):10-2.
HLA genes and their products are of central importance for the development of autoimmune diseases. HLA antigens influence the immune repertoire of T cells and therefore all immune responses are HLA dependent. Research in molecular genetics have helped to identify both HLA genes and specific T cell clones involved in autoimmune reactions, which create possibilities of immune intervention.
HLA基因及其产物对于自身免疫性疾病的发展至关重要。HLA抗原影响T细胞的免疫库，因此所有免疫反应均依赖于HLA。分子遗传学研究有助于识别参与自身免疫反应的HLA基因和特定T细胞克隆，这为免疫干预创造了可能性。
