Cahill Kevin
Biophysics Group, Department of Physics & Astronomy, University of New Mexico, Albuquerque, New Mexico 87131, USA.
Phys Rev E Stat Nonlin Soft Matter Phys. 2012 May;85(5 Pt 1):051921. doi: 10.1103/PhysRevE.85.051921. Epub 2012 May 29.
Formulas are derived for the electrostatic potential of a charge in or near a membrane modeled as one or more dielectric slabs lying between two semi-infinite dielectrics. One can use these formulas in Monte Carlo codes to compute the distribution of ions near cell membranes more accurately than by using Poisson-Boltzmann theory or its linearized version. Here I use them to discuss the electric field of a uniformly charged membrane, the image charges of an ion, the distribution of salt ions near a charged membrane, the energy of a zwitterion near a lipid slab, and the effect of including the phosphate head groups as thin layers of high electric permittivity.
推导出了电荷在模拟为位于两个半无限电介质之间的一个或多个电介质平板的膜内或膜附近的静电势公式。与使用泊松 - 玻尔兹曼理论或其线性化版本相比，人们可以在蒙特卡罗代码中使用这些公式更准确地计算细胞膜附近离子的分布。在此，我用它们来讨论均匀带电膜的电场、离子的镜像电荷、带电膜附近盐离子的分布、两性离子在脂质平板附近的能量，以及将磷酸头部基团视为高介电常数薄层的影响。
