Division of Hematology, Department of Medicine, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA.
Hematol Oncol Clin North Am. 2012 Oct;26(5):1117-28. doi: 10.1016/j.hoc.2012.08.001.
The clinical presentation of mastocytosis is diverse, and patients may not fit the classical description. Diagnosis requires a bone marrow examination, including immunohistochemical stains for mast cell tryptase or CD117. The treatment of adult systemic mastocytosis is highly individualized. This article presents an overview of systemic mastocytosis and describes its pathogenesis and treatment.
肥大细胞增多症的临床表现多种多样，患者可能不符合经典描述。诊断需要进行骨髓检查，包括肥大细胞胰蛋白酶或 CD117 的免疫组织化学染色。成人系统性肥大细胞增多症的治疗具有高度个体性。本文概述了系统性肥大细胞增多症，并描述了其发病机制和治疗方法。
