Department of Chemistry, Shahid Bahonar University of Kerman, P.O. Box 76175-133, Kerman, Iran.
Colloids Surf B Biointerfaces. 2013 Feb 1;102:385-90. doi: 10.1016/j.colsurfb.2012.08.022. Epub 2012 Aug 24.
A novel 1-benzyl-4-ferrocenyl-1H-[1,2,3]-triazole (BFT)/carbon nanotube modified glassy carbon electrode (BFT-CNT-GCE) was prepared for the simultaneous determination of N-acetylcysteine (NAC) and folic acid (FA). Cyclic voltammetry (CV), chronoamperometry (CHA), and square wave voltammetry (SWV) methods were used to investigate the modified electrode for the electrocatalytic oxidation of NAC and FA in aqueous solutions. The separation of the oxidation peak potentials for NAC-FA was about 280 mV. The calibration curve obtained for NAC was in the range of 0.1-600.0 μM. The detection limit (S/N=3) was 62.0±2.0 nM for NAC. The diffusion coefficient and the catalytic rate constant for the oxidation of NAC at the modified electrode were calculated as (3.5±0.2)×10(-5) cm(2) s(-1) and (9.85±0.4)×10(-4) M(-1) s(-1), respectively. The method was employed for the determination of NAC and FA in some real samples.
一种新型的 1-苄基-4-二茂铁基-1H-[1,2,3]-三唑（BFT）/碳纳米管修饰玻碳电极（BFT-CNT-GCE）被制备用于同时测定 N-乙酰半胱氨酸（NAC）和叶酸（FA）。循环伏安法（CV）、计时安培法（CHA）和方波伏安法（SWV）被用于研究修饰电极对水溶液中 NAC 和 FA 的电催化氧化作用。NAC-FA 的氧化峰电位分离约为 280 mV。NAC 的校准曲线范围为 0.1-600.0 μM。NAC 的检测限（S/N=3）为 62.0±2.0 nM。在修饰电极上氧化 NAC 的扩散系数和催化速率常数分别计算为（3.5±0.2）×10(-5) cm(2) s(-1)和（9.85±0.4）×10(-4) M(-1) s(-1)。该方法用于一些实际样品中 NAC 和 FA 的测定。
