[脂肪硬化性黏液纤维瘤继发的毛细血管扩张性骨肉瘤：1例报告]

[Telangiectatic osteosarcoma secondary to a liposclerosing myxofibrous tumor: a case report].

作者信息

Illac Claire, Delisle Marie-Bernadette, Bonnevialle Paul, Chiavassa-Gandois Hélène, de Pinieux Gonzague, Gomez-Brouchet Anne

机构信息

Service d'anatomie pathologique et histologie-cytologie, CHU de Rangueil, 1, avenue du Professeur-Jean-Poulhès, TSA 50032, 31059 Toulouse cedex 9, France.

出版信息

Ann Pathol. 2012 Aug;32(4):259-62. doi: 10.1016/j.annpat.2012.06.003. Epub 2012 Jul 21.

DOI:10.1016/j.annpat.2012.06.003

PMID:23010399

Abstract

Malignant transformation of a fibrous dysplasia into an osteosarcoma is very rare. We report the case of an 84-year-old man with telangiectatic osteosarcoma of the upper femur arising in a previous fibrous dysplasia also known as liposclerosing myxofibrous tumor. The tumor was expressing the epithelial membrane antigen. This is the first described case of a malignant transformation into an osteosarcoma arising in a liposclerosing myxofibrous tumor. We discuss the main differential diagnosis with a review.

摘要

骨纤维发育不良恶变为骨肉瘤非常罕见。我们报告一例84岁男性，其股骨上段的毛细血管扩张型骨肉瘤发生于先前的骨纤维发育不良，也称为脂肪硬化性黏液纤维瘤。该肿瘤表达上皮膜抗原。这是首例报道的脂肪硬化性黏液纤维瘤恶变为骨肉瘤的病例。我们通过文献回顾讨论了主要的鉴别诊断。