Wang Fen, Li Run-Hua, Yin Guo-Rong
Department of Parasitology, Shanxi Medical University, Taiyuan 030001, China.
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2012 Jun;24(3):353-7.
Phosphoglycerate mutase (PGAM) is one of glycolytic enzymes, concerning with the transport of carbohydrates, metabolism, catalytic activity and growth development. PGAM was discovered in yeast firstly, and with its amino acid sequence and crystal structure determined, this protein was found in varies organism, such as human, Escherichia coli, Schistosoma japonicum and Toxoplasma gondii. This article reviews the physico-chemical property and research progress of PGAM of vertebrate, invertebrate and protozoa.
磷酸甘油酸变位酶(PGAM)是糖酵解酶之一,与碳水化合物的运输、代谢、催化活性及生长发育有关。PGAM最早在酵母中被发现,随着其氨基酸序列和晶体结构的确定,该蛋白在多种生物体中被发现,如人类、大肠杆菌、日本血吸虫和弓形虫。本文综述了脊椎动物、无脊椎动物和原生动物PGAM的理化性质及研究进展。