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多形红斑的误诊:文献综述与病例报告

Misdiagnosis of erythema multiforme: a literature review and case report.

作者信息

Kempton John, Wright John M, Kerins Carolyn, Hale David

机构信息

Department of Diagnostic Sciences, Baylor College of Dentistry, The Texas A&M University System, Health Science Center, Dallas, Texas, USA.

出版信息

Pediatr Dent. 2012 Jul-Aug;34(4):337-42.

PMID:23014092
Abstract

Erythema multiforme is primarily considered a disease of the skin. Diagnosis tends to be centered on dermatologic lesions of the extremities, with mouth ulcers regarded as a secondary finding. The purpose of this paper was to report a case of an 8-year-old male diagnosed with erythema multiforme limited to the oral cavity. The patient was referred to Texas A&M Health Science Center's Baylor College of Dentistry for biopsy of recurrent mouth ulcers following an outbreak of a fever blister. Previous hospitalization occurred twice due to severe mouth ulcers causing dehydration and loss of nutrition. He was treated with 10 mg of prednisone twice daily and was able to eat and drink without pain within 48 hours. Nearly all lesions healed within 5 days of therapy. Although rare, erythema multiforme should always be considered in the differential diagnosis in the event of acute onset stomatitis.

摘要

多形红斑主要被认为是一种皮肤疾病。诊断往往集中在四肢的皮肤病变上,口腔溃疡被视为次要表现。本文的目的是报告一例8岁男性被诊断为仅限于口腔的多形红斑病例。该患者因唇疱疹发作后反复出现口腔溃疡,被转诊至德克萨斯农工大学健康科学中心的贝勒牙科学院进行活检。此前曾因严重口腔溃疡导致脱水和营养流失而住院两次。他接受了每日两次、每次10毫克泼尼松的治疗,48小时内就能无痛进食和饮水。几乎所有病变在治疗5天内愈合。尽管罕见,但在急性发作性口腔炎的鉴别诊断中,应始终考虑多形红斑。

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