• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

药物技术中的固体分散体。第二部分。固体分散体的分析方法及其应用实例。

Solid dispersion in pharmaceutical technology. Part II. The methods of analysis of solid dispersions and examples of their application.

作者信息

Karolewicz Bozena, Górniak Agata, Owczarek Artur, Nartowski Karol, Zurawska-Płaksej Ewa, Pluta Janusz

机构信息

Department of Drug Form Technology, Wroclaw Medical University, Wroclaw, Poland.

出版信息

Polim Med. 2012;42(2):97-107.

PMID:23016440
Abstract

In the first part of the article solid dispersions were classified the properties and methods of their preparation were described. This section presents methods of analysis of solid dispersions i.e.: thermoanalytical methods, XRPD, FTIR, microscopic methods, dissolution studies and examples of drug forms where solid dispersions were used.

摘要

在文章的第一部分,对固体分散体进行了分类,并描述了其制备性质和方法。本节介绍了固体分散体的分析方法,即:热分析方法、X射线粉末衍射法(XRPD)、傅里叶变换红外光谱法(FTIR)、显微镜方法、溶出度研究以及使用固体分散体的药物剂型实例。

相似文献

1
Solid dispersion in pharmaceutical technology. Part II. The methods of analysis of solid dispersions and examples of their application.药物技术中的固体分散体。第二部分。固体分散体的分析方法及其应用实例。
Polim Med. 2012;42(2):97-107.
2
Preparation, characterization and tableting of cilnidipine solid dispersions.西尼地平固体分散体的制备、表征及压片
Pak J Pharm Sci. 2013 May;26(3):629-36.
3
Enhancement of dissolution profile by solid dispersion (kneading) technique.采用固体分散体(捏合)技术提高溶出度曲线
AAPS PharmSciTech. 2006 Aug 18;7(3):68. doi: 10.1208/pt070368.
4
Study on Enhanced Dissolution of Azilsartan-Loaded Solid Dispersion, Prepared by Combining Wet Milling and Spray-Drying Technologies.采用湿磨和喷雾干燥技术联合制备阿齐沙坦固体分散体的增溶研究
AAPS PharmSciTech. 2017 Feb;18(2):473-480. doi: 10.1208/s12249-016-0531-1. Epub 2016 Apr 26.
5
Effect of Compression on the Molecular Arrangement of Itraconazole-Soluplus Solid Dispersions: Induction of Liquid Crystals or Exacerbation of Phase Separation?压缩对伊曲康唑 - 固体分散体分子排列的影响:诱导液晶形成还是加剧相分离?
Mol Pharm. 2016 Jun 6;13(6):1879-93. doi: 10.1021/acs.molpharmaceut.6b00046. Epub 2016 May 4.
6
Effect of drug-carrier interaction on the dissolution behavior of solid dispersion tablets.载药相互作用对固体分散体片溶出行为的影响。
Pharm Dev Technol. 2010 Sep-Oct;15(5):460-8. doi: 10.3109/10837450903286529.
7
Application of Solid Dispersion Technique to Improve Solubility and Sustain Release of Emamectin Benzoate.固体分散技术在提高甲氨基阿维菌素苯甲酸盐溶解度和持续释放中的应用。
Molecules. 2019 Nov 26;24(23):4315. doi: 10.3390/molecules24234315.
8
Triboelectrification and dissolution property enhancements of solid dispersions.固体分散体的摩擦起电及溶解性能增强
Int J Pharm. 2015 May 15;485(1-2):306-16. doi: 10.1016/j.ijpharm.2015.03.013. Epub 2015 Mar 12.
9
Crystallinity evaluation of tacrolimus solid dispersions by chemometric analysis.通过化学计量分析评估他克莫司固体分散体的结晶度。
Int J Pharm. 2012 Feb 28;423(2):341-50. doi: 10.1016/j.ijpharm.2011.11.003. Epub 2011 Nov 12.
10
Raman and thermal analysis of indomethacin/PVP solid dispersion enteric microparticles.吲哚美辛/PVP固体分散体肠溶微粒的拉曼光谱与热分析
Eur J Pharm Biopharm. 2008 Sep;70(1):409-20. doi: 10.1016/j.ejpb.2008.03.016. Epub 2008 Apr 8.

引用本文的文献

1
Solid Dispersions Obtained by Ball Milling as Delivery Platform of Etodolac, a Model Poorly Soluble Drug.通过球磨法获得的固体分散体作为依托度酸(一种典型的难溶性药物)的给药平台
Materials (Basel). 2024 Aug 7;17(16):3923. doi: 10.3390/ma17163923.
2
Recent Patents on Solid Dispersions Emphasize Promising Benefits in Solubility Enhancement of Poorly Water-soluble Drugs.固体分散体的最新专利强调了在提高难溶性药物溶解度方面的显著优势。
Recent Pat Nanotechnol. 2025;19(2):216-240. doi: 10.2174/0118722105229356231030065938.