Green M F, Nuechterlein K H, Ventura J, Mintz J
Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles.
Am J Psychiatry. 1990 Feb;147(2):179-82. doi: 10.1176/ajp.147.2.179.
The authors examined the temporal relationship between onset of depressive and psychotic symptoms in 27 patients with recent-onset schizophrenia or schizo-affective disorder. Ratings on the Brief Psychiatric Rating Scale were collected every 2 weeks for at least 1 year to specify onset of relapse or exacerbation. Six time periods were defined in relation to onset of psychotic symptoms, and the number of depressive periods was determined for each time period. Onset of depressive periods was concurrent with onset of psychosis more often than expected but was not associated with any other time period. The authors found no distinctive postpsychotic pattern of onset for depression.
作者研究了27例近期起病的精神分裂症或分裂情感性障碍患者抑郁症状和精神病性症状发作之间的时间关系。每2周收集一次简明精神病评定量表评分，至少持续1年，以明确复发或病情加重的发作情况。根据精神病性症状发作确定了六个时间段，并确定每个时间段的抑郁发作次数。抑郁发作与精神病发作同时出现的情况比预期更为常见，但与其他任何时间段均无关联。作者未发现抑郁症有明显的精神病发作后发病模式。
