Australian Centre for Economic Research on Health, The University of Queensland, Herston, Queensland 4029, Australia.
J Clin Epidemiol. 2012 Nov;65(11):1219-26. doi: 10.1016/j.jclinepi.2012.05.012.
This study highlights the serious consequences of ignoring reverse causality bias in studies on compensation-related factors and health outcomes and demonstrates a technique for resolving this problem of observational data.
Data from an English longitudinal study on factors, including claims for compensation, associated with recovery from neck pain (whiplash) after rear-end collisions are used to demonstrate the potential for reverse causality bias. Although it is commonly believed that claiming compensation leads to worse recovery, it is also possible that poor recovery may lead to compensation claims--a point that is seldom considered and never addressed empirically. This pedagogical study compares the association between compensation claiming and recovery when reverse causality bias is ignored and when it is addressed, controlling for the same observable factors.
When reverse causality is ignored, claimants appear to have a worse recovery than nonclaimants; however, when reverse causality bias is addressed, claiming compensation appears to have a beneficial effect on recovery, ceteris paribus.
To avert biased policy and judicial decisions that might inadvertently disadvantage people with compensable injuries, there is an urgent need for researchers to address reverse causality bias in studies on compensation-related factors and health.
本研究强调了在研究与赔偿相关因素和健康结果时忽略反向因果关系偏差的严重后果,并展示了一种解决观察性数据中这一问题的技术。
使用来自英国一项关于与追尾碰撞后颈部疼痛(挥鞭伤)恢复相关因素(包括赔偿要求)的纵向研究的数据,来说明反向因果关系偏差的潜在可能性。尽管人们普遍认为索赔赔偿会导致更糟糕的恢复,但也有可能是恢复不佳导致了赔偿要求——这一点很少被考虑,也从未在实证上得到解决。本教学研究比较了当忽略和解决反向因果关系偏差时,索赔与恢复之间的关联,同时控制了相同的可观察因素。
当忽略反向因果关系时,索赔者的恢复似乎比非索赔者差;然而,当解决反向因果关系偏差时,在其他条件相同的情况下,索赔赔偿似乎对恢复有有益的影响。
为了避免可能无意中使可赔偿伤害的人处于不利地位的有偏见的政策和司法决策,研究人员迫切需要在与赔偿相关因素和健康相关的研究中解决反向因果关系偏差问题。