Bubonic plague in a child presenting with fever and altered mental status.

An 8-year-old Navajo boy presented to the emergency department with fever and altered mental status. Because the child lived in a plague-endemic area of the southwestern United States, antibiotics effective against Yersinia pestis were administered rapidly. Buboes were appreciated on physical examination, and the diagnosis of bubonic plague was confirmed by positive blood cultures. Characteristics and treatment of Yersinia pestis infection are discussed. The need for a high index of suspicion for the presence of plague in patients who present to the ED and who reside or have recently traveled in a plague-endemic area is emphasized.