Woolcock Institute of Medical Research, Glebe, N.S.W., Department of Respiratory Medicine, Royal North Shore Hospital, St. Leonards, N.S.W., Australia.
Respiration. 2012;84(4):265-74. doi: 10.1159/000342645. Epub 2012 Sep 27.
Three-dimensional lung imaging has become a routine investigation in clinical medicine. The clinical needs have driven the development of tomographic imaging, as much as the research into better imaging itself has driven some of the improvements in imaging. There has been a steady stream of publications in which tomographic imaging has been used to measure small airway structure and function in obstructive airway diseases. These data provide unique insights and information on pulmonary physiology because they provide direct measurements of the airways, rather than global information from lung function, and they provide topographical information, i.e. spatial distribution. Their utility is magnified when combined with other information such as lung function. In this article, the application of topographic imaging in relation to small airway function is discussed.
三维肺部成像已成为临床医学中的常规检查。临床需求推动了断层成像的发展，而对更好成像的研究也推动了成像的一些改进。已经有大量的出版物使用断层成像来测量阻塞性气道疾病中小气道的结构和功能。这些数据提供了关于肺生理学的独特见解和信息，因为它们提供了气道的直接测量值，而不是来自肺功能的整体信息，并且它们提供了地形信息，即空间分布。当与其他信息（如肺功能）结合使用时，它们的效用会放大。本文讨论了与小气道功能相关的地形成像的应用。
