Houston L, Sullivan S
Department of Obstetrics and Gynecology, Medical University of South Carolina, Charleston, SC, USA.
Minerva Ginecol. 2012 Oct;64(5):409-19.
Pregnancy in a patient with Marfan syndrome may pose significant maternal and fetal risks, and pregnancy outcome is most impacted by the extent of cardiovascular involvement present at conception. This review addresses principles to guide preconception counseling of a Marfan patient, in addition to antepartum and intrapartum management considerations. Multidisciplinary care is recommended during pregnancy, given the potential for multiorgan involvement and various complications which may occur. Mode of delivery planning is guided by the degree of aortic root dilatation. Dissection of a dilated aortic root can present a surgical emergency during pregnancy, and principles for cardiopulmonary bypass in a pregnant patient are reviewed.
患有马凡综合征的患者怀孕可能会给母亲和胎儿带来重大风险，而怀孕结局受受孕时心血管受累程度的影响最大。本综述阐述了指导马凡综合征患者孕前咨询的原则，以及产前和产时管理的注意事项。鉴于孕期可能出现多器官受累和各种并发症，建议采用多学科护理。分娩方式的规划取决于主动脉根部扩张的程度。扩张的主动脉根部夹层在孕期可能会引发外科急症，本文还综述了孕妇体外循环的原则。
