Thorax. 2012 Dec;67(12):1028-31. doi: 10.1136/thoraxjnl-2012-202628. Epub 2012 Sep 27.
The Montreal Protocol was signed 25 years ago. As a result, the irreversible destruction of the ozone layer was prevented. However, stratospheric ozone will not recover completely until 2060 and the consequent epidemic in skin cancer cases will persist until 2100. Many millions of patients with asthma and chronic obstructive pulmonary disease have safely switched from chlorofluorocarbon (CFC)-powered metered-dose inhalers (MDIs) to either hydrofluorocarbon (HFC) or DPIs. China will be the last country to phase out CFCs by 2016. HFCs are global warming gases which will be controlled in the near future. HFCs in MDIs may be phased out over the next 10-20 years.
《蒙特利尔议定书》签署至今已有 25 年。该议定书的签署，阻止了臭氧层的不可逆破坏。然而，平流层臭氧要到 2060 年才能完全恢复，随之而来的皮肤癌病例也将持续到 2100 年。数以百万计的哮喘和慢性阻塞性肺病患者已从氯氟烃（CFC）驱动的计量吸入器（MDI）安全切换至氢氟碳化物（HFC）或干粉吸入器（DPI）。中国将于 2016 年成为最后一个淘汰 CFC 的国家。HFC 是温室气体，在不久的将来将受到控制。MDI 中的 HFC 可能在未来 10-20 年内逐步淘汰。
