Heinrich-Heine-Universität Düsseldorf, Institut für Organische Chemie und Macromolekulare Chemie, Universitätsstraße 1, 40225 Düsseldorf, Germany.
Beilstein J Org Chem. 2012;8:1528-35. doi: 10.3762/bjoc.8.173. Epub 2012 Sep 13.
A macromonomer 5 consisting of a polymerizable vinylcyclopropane end group and a poly(N-isopropylacrylamide) (poly(NiPAAm)) chain was obtained from amidation of 1-ethoxycarbonyl-2-vinylcyclopropane-1-carboxylic acid (4) with an amino-terminated poly(NiPAAm) 3 as an example. This macromonomer 5 showed an LCST effect after complexation of the vinyl end group with ß-cyclodextrin in water. Via radical ring-opening copolymerization of 5 and NiPAAm a graft copolymer 8 with a clouding point of 32 °C was synthesized. The branched unsaturated polymer was treated with ozone to cleave the double bonds of the main chain.
以酰胺化 1-乙氧羰基-2-乙烯基环丙烷-1-羧酸（4）与端氨基聚（N-异丙基丙烯酰胺）3 为例，得到了一种由可聚合的乙烯基环丙烷端基和聚（N-异丙基丙烯酰胺）（poly（NiPAAm））链组成的大分子单体 5。这种大分子单体 5 在水与β-环糊精络合后表现出 LCST 效应。通过自由基开环共聚 5 和 NiPAAm，合成了浊点为 32°C 的接枝共聚物 8。支化的不饱和聚合物用臭氧处理，以切断主链的双键。
