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与牙瘤相关的牙源性幽灵细胞瘤——两例罕见病例报告

Ghost cell odontogenic tumor associated with odontoma--report of two rare cases.

作者信息

Hogge Maritzabel, Velez Ines, Kaltman Steven, Movahed Reza, Yeh Frank

机构信息

Radiology Division, Nova Southeastern University, College of Dental Medicine, Fort Lauderdale, Fl 33328, USA.

出版信息

J Clin Pediatr Dent. 2012 Summer;36(4):373-6. doi: 10.17796/jcpd.36.4.h0x50662vj624912.

Abstract

The ghost cell odontogenic tumor (GCOT) is a neoplastic/cystic lesion with a diverse histopathological and clinical behavior It was formerly known as calcified odontogenic cyst, but in 2005 the World Health Organization categorized this lesion as an odontogenic, benign tumor rather than a cyst; nominating this neoplasm as calcifying cystic odontogenic tumor. A later comprehensive classification named it ghost cell odontogenic tumor because the most remarkable histopathologic characteristic is the presence of a mass of ghost cells embedded in the epithelium. We report two cases of a rare variant of a ghost cell odontogenic tumor associated with odontoma; to our knowledge, one is the youngest patient (four month old) reported in the English literature.

摘要

幽灵细胞牙源性肿瘤(GCOT)是一种具有多样组织病理学和临床行为的肿瘤性/囊性病变。它以前被称为钙化牙源性囊肿,但在2005年世界卫生组织将该病变归类为牙源性良性肿瘤而非囊肿;将这种肿瘤命名为钙化囊性牙源性肿瘤。后来的一个综合分类将其命名为幽灵细胞牙源性肿瘤,因为最显著的组织病理学特征是上皮内存在大量幽灵细胞。我们报告了两例与牙瘤相关的罕见变异型幽灵细胞牙源性肿瘤病例;据我们所知,其中一例是英文文献中报道的最年轻患者(四个月大)。

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