Hogge Maritzabel, Velez Ines, Kaltman Steven, Movahed Reza, Yeh Frank
Radiology Division, Nova Southeastern University, College of Dental Medicine, Fort Lauderdale, Fl 33328, USA.
J Clin Pediatr Dent. 2012 Summer;36(4):373-6. doi: 10.17796/jcpd.36.4.h0x50662vj624912.
The ghost cell odontogenic tumor (GCOT) is a neoplastic/cystic lesion with a diverse histopathological and clinical behavior It was formerly known as calcified odontogenic cyst, but in 2005 the World Health Organization categorized this lesion as an odontogenic, benign tumor rather than a cyst; nominating this neoplasm as calcifying cystic odontogenic tumor. A later comprehensive classification named it ghost cell odontogenic tumor because the most remarkable histopathologic characteristic is the presence of a mass of ghost cells embedded in the epithelium. We report two cases of a rare variant of a ghost cell odontogenic tumor associated with odontoma; to our knowledge, one is the youngest patient (four month old) reported in the English literature.
幽灵细胞牙源性肿瘤(GCOT)是一种具有多样组织病理学和临床行为的肿瘤性/囊性病变。它以前被称为钙化牙源性囊肿,但在2005年世界卫生组织将该病变归类为牙源性良性肿瘤而非囊肿;将这种肿瘤命名为钙化囊性牙源性肿瘤。后来的一个综合分类将其命名为幽灵细胞牙源性肿瘤,因为最显著的组织病理学特征是上皮内存在大量幽灵细胞。我们报告了两例与牙瘤相关的罕见变异型幽灵细胞牙源性肿瘤病例;据我们所知,其中一例是英文文献中报道的最年轻患者(四个月大)。