Tabatabaie-Zadeh Seyyed Abolfazl, Saebnoori Homeira
School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Department of Oral and Maxillofacial Pathology, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Int J Surg Case Rep. 2023 Apr;105:107991. doi: 10.1016/j.ijscr.2023.107991. Epub 2023 Mar 24.
Odontogenic lesions composed of two or more separate odontogenic cysts are uncommon. The calcifying odontogenic cyst (COC) and odontogenic keratocyst (OKC) are odontogenic cysts that exhibit some neoplastic features. Concurrence of these lesions is extremely rare. We report a rare case of COC combined with OKC in a patient and review the relevant literature systemically.
In this article, we present a case report of an 18-year-old boy patient with no medical history whose chief complaint was facial asymmetry. A painless swelling in the right side of the posterior mandible was observed. Histopathological and radiographic investigations revealed a combined odontogenic lesion composed of inflamed OKC with COC.
Long-lasting debates on the true nature of OKC and COC, whether cystic or neoplastic, has been existed so far. Their genetic-derived mechanisms can justify the concurrent occurrence of these cysts in a patient. The treatment plan for this lesion included decompression followed by enucleation, curettage, and application of Carnoy's solution.
We reported a rare case of an inflamed OKC with COC-like features. Based on the literature, the coincidence of these two odontogenic cysts has been reported for the third time here.
由两个或更多个独立牙源性囊肿组成的牙源性病变并不常见。钙化牙源性囊肿（COC）和牙源性角化囊肿（OKC）是具有一些肿瘤特征的牙源性囊肿。这些病变同时出现极为罕见。我们报告一例患者中COC合并OKC的罕见病例，并对相关文献进行系统回顾。
在本文中，我们报告一例18岁男性患者的病例，该患者无病史，主要诉求为面部不对称。观察到下颌骨后部右侧有一无痛性肿胀。组织病理学和影像学检查显示为一种由伴有COC的炎症性OKC组成的联合牙源性病变。
关于OKC和COC的真正性质，无论是囊性还是肿瘤性，至今一直存在长期争论。它们的遗传衍生机制可以解释这些囊肿在一名患者中同时出现的情况。该病变的治疗方案包括减压，随后进行摘除、刮除，并应用卡诺氏液。
我们报告了一例具有COC样特征的炎症性OKC罕见病例。根据文献，这两种牙源性囊肿的巧合在此处是第三次被报道。
