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妊娠24周前胎膜早破(PROM)后新生儿良好结局的决定因素——文献综述及病例报告

Determinants of favourable neonatal outcome after premature rupture of membranes (PROM) before 24 weeks of pregnancy--review of the literature and a case report.

作者信息

Chmaj-Wierzchowska Karolina, Pięta Beata, Buks Joanna, Wierzchowski Marcin, Opala Tomasz

机构信息

Department of Mother's and Child's Health, University of Medical Sciences, Poznan, Poland.

出版信息

Ann Agric Environ Med. 2012;19(3):577-80.

PMID:23020060
Abstract

OBJECTIVES

Premature rupture of the membranes (PROM) in pregnancy refers to rupture of membranes of the amniotic sac and chorion. The aim of the study was to review the literature and analyze the course of pregnancy (primipara) complicated by the premature rupture of the membranes, and consequent loss of amniotic fluid after 19 weeks of gestation.

STUDY DESIGN

A 27-year old primiparous patient was admitted to the Gynaecology and Obstetrics University Hospital in Poznań on 9 December 2010, due to suspected premature rupture of the membranes. On presentation, foetal development was at 19 weeks gestation. Standard clinical investigations included ultrasonography, amniotic fluid index measurements and laboratory blood tests.

RESULTS

Ultrasonography confirmed the size of the foetus to be normal for the gestational age. However, no amniotic fluid pockets were visible and the amniotic fluid index was 0 cm. The patient was hospitalized on multiple occasions and as a result a decision was made to end the pregnancy prematurely by means of a caesarean section at 32 weeks of gestation. Longer-term observation of the newborn indicated that one year following delivery, the development of the baby was normal, and thus far no neurological injuries or complications have been observed.

CONCLUSION

The pregnancy was ultimately successfully completed with the delivery of a healthy newborn at 32 weeks of gestation. A regime involving rigorous bed rest and antibiotic administration can positively extend the duration of pregnancies complicated by premature rupture of the membranes.

摘要

目的

孕期胎膜早破(PROM)是指羊膜囊和绒毛膜的胎膜破裂。本研究的目的是回顾文献并分析妊娠过程(初产妇)合并胎膜早破以及妊娠19周后羊水流失的情况。

研究设计

一名27岁的初产妇于2010年12月9日因疑似胎膜早破入住波兹南大学妇产医院。就诊时,胎儿发育处于妊娠19周。标准临床检查包括超声检查、羊水指数测量和实验室血液检查。

结果

超声检查证实胎儿大小与孕周相符。然而,未见羊水暗区,羊水指数为0厘米。患者多次住院,因此决定在妊娠32周时通过剖宫产提前终止妊娠。对新生儿的长期观察表明,分娩一年后,婴儿发育正常,迄今为止未观察到神经损伤或并发症。

结论

妊娠最终在妊娠32周时成功完成,分娩出一名健康的新生儿。严格卧床休息和使用抗生素的方案可以有效地延长合并胎膜早破的妊娠时间。

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