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Mini test dose of intravenous busulfan (busulfex(®)) in allogeneic non-myeloablative stem cell transplantation, followed by liquid chromatography tandem-mass spectrometry.

作者信息

Spasojevic Ivan, da Costa Ligia R S, Horwitz Mitchell E, Long Gwynn D, Sullivan Keith M, Chute John P, Gasparetto Cristina, Morris Ashley, Chao Nelson J, Rizzieri David A

机构信息

Department of Medicine, Division of Oncology, Duke University Medical Center, Durham, NC, USA.

出版信息

Cancer Invest. 2012 Nov;30(9):679-82. doi: 10.3109/07357907.2012.726386. Epub 2012 Sep 28.

DOI:10.3109/07357907.2012.726386
PMID:23020519
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3791921/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e927/3791921/d00d927f642f/nihms514999f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e927/3791921/3124a328e784/nihms514999f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e927/3791921/d00d927f642f/nihms514999f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e927/3791921/3124a328e784/nihms514999f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e927/3791921/d00d927f642f/nihms514999f2.jpg

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Mini test dose of intravenous busulfan (busulfex(®)) in allogeneic non-myeloablative stem cell transplantation, followed by liquid chromatography tandem-mass spectrometry.异基因非清髓性干细胞移植中静脉注射小剂量白消安（白舒非（®）），随后进行液相色谱串联质谱分析。
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本文引用的文献

1
Reliability of a pretransplant i.v. BU test dose performed 2 weeks before myeloablative FluBu conditioning regimen.在接受清髓性 FluBu 预处理方案前 2 周进行的静脉 BU 试验剂量的可靠性。
Bone Marrow Transplant. 2010 Feb;45(2):249-53. doi: 10.1038/bmt.2009.133. Epub 2009 Jun 22.
2
Busulfan in hematopoietic stem cell transplantation.白消安在造血干细胞移植中的应用
Biol Blood Marrow Transplant. 2009 May;15(5):523-36. doi: 10.1016/j.bbmt.2008.12.489. Epub 2009 Feb 12.
3
Therapeutic drug monitoring of busulfan in transplantation.移植中白消安的治疗药物监测
Curr Pharm Des. 2008;14(20):1936-49. doi: 10.2174/138161208785061382.
4
Home administration of high-dose oral busulfan in patients undergoing hematopoietic stem cell transplantation.造血干细胞移植患者高剂量口服白消安的居家给药
Bone Marrow Transplant. 2007 Apr;39(7):397-400. doi: 10.1038/sj.bmt.1705610. Epub 2007 Feb 26.
5
Development of a rapid and specific assay for detection of busulfan in human plasma by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry.高效液相色谱/电喷雾电离串联质谱法快速、特异性检测人血浆中白消安分析方法的建立。
Rapid Commun Mass Spectrom. 2005;19(12):1666-74. doi: 10.1002/rcm.1962.
6
Acute safety and pharmacokinetics of intravenous busulfan when used with oral busulfan and cyclophosphamide as pretransplantation conditioning therapy: a phase I study.静脉注射白消安与口服白消安及环磷酰胺联合用于移植前预处理治疗时的急性安全性和药代动力学：一项I期研究。
Biol Blood Marrow Transplant. 2000;6(5A):548-54. doi: 10.1016/s1083-8791(00)70064-4.
7
Plasma concentration monitoring of busulfan: does it improve clinical outcome?白消安的血药浓度监测：它能改善临床结局吗？
Clin Pharmacokinet. 2000 Aug;39(2):155-65. doi: 10.2165/00003088-200039020-00005.
8
Marrow transplantation for chronic myeloid leukemia: the influence of plasma busulfan levels on the outcome of transplantation.
Blood. 1997 Apr 15;89(8):3055-60.
9
Aspects concerning busulfan pharmacokinetics and bioavailability.
Leuk Lymphoma. 1996 Aug;22(5-6):395-407. doi: 10.3109/10428199609054777.
10
Association of busulfan area under the curve with veno-occlusive disease following BMT.白消安曲线下面积与骨髓移植后静脉闭塞性疾病的关联。
Bone Marrow Transplant. 1996 Feb;17(2):225-30.