State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China.
Chem Commun (Camb). 2012 Nov 14;48(88):10859-61. doi: 10.1039/c2cc35819k. Epub 2012 Oct 1.
It is proposed that direct electron transfer is dependent on the orientation of the heme plane in cytochrome c (cyt c) assembled on electrode surfaces. Orientation with the heme plane in cyt c parallel to the gold electrode surface favors the direct electron transfer, while vertical orientation of the heme plane makes the direct electron transfer difficult. A preferable electron transport pathway for cyt c is through the axial ligand (His-18) of the heme center rather than the porphyrin ring.
有人提出，细胞色素 c（cyt c）在电极表面组装时，其血红素平面的取向决定了直接电子转移是否发生。当血红素平面与金电极表面平行时，有利于直接电子转移，而当血红素平面垂直时，直接电子转移则变得困难。对于 cyt c，一个更可取的电子传输途径是通过血红素中心的轴向配体（His-18），而不是卟啉环。
