Niikura Takahiro, Lee Sang Yang, Oe Keisuke, Koh Akihiro, Koga Takaaki, Dogaki Yoshihiro, Okumachi Etsuko, Sakai Yoshitada, Akisue Toshihiro, Kuroda Ryosuke, Kurosaka Masahiro
Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Orthopedics. 2012 Oct;35(10):e1476-82. doi: 10.3928/01477447-20120919-15.
Fractures occurring at the distal part of the lower extremities are recognized to have a relatively lower risk of venous thromboembolism (VTE); however, few detailed reports exist on the subject. The purpose of this study was to investigate the incidence of VTE in fractures around and below the knee. Overall, 109 consecutive patients with fractures around and below the knee who were surgically treated at the authors' hospital were analyzed retrospectively. Physical prophylaxis was performed in all patients. Until April 2009, VTE screening was performed by contrast-enhanced computed tomography or ultrasonography when the D-dimer value did not decline predictably, exceeded 20 μg/mL 5 days after trauma and surgery, or increased above 20 μg/mL after a period of decline. After April 2009, ultrasonography was routinely performed pre- and postoperatively irrespective of the D-dimer value. The patients were divided into 2 groups based on the absence or presence of accompanying injuries, including head, chest, abdominal, or spinal injury and other fractures of the pelvis and lower extremities. Overall, VTE and pulmonary thromboembolism were detected in 28 (25.7%) patients and 5 (4.6%) patients, respectively. All cases were asymptomatic. The VTE incidence rates were 8.6% (former screening) and 40% (newer screening) in patients with isolated fractures and 25% (former screening) and 41.7% (newer screening) in patients with accompanying injuries. The pulmonary thromboembolism incidence rates were 2.9% (former screening) and 0% (newer screening) in patients with isolated fractures and 3.2% (former screening) and 25.0% (newer screening) in patients with accompanying injuries. Surgeons should be vigilant for symptoms of VTE in patients with fractures occurring at the distal part of the lower extremities.
下肢远端发生的骨折被认为发生静脉血栓栓塞(VTE)的风险相对较低;然而,关于这一主题的详细报告很少。本研究的目的是调查膝关节周围及以下骨折中VTE的发生率。总体而言,对作者所在医院接受手术治疗的109例连续膝关节周围及以下骨折患者进行了回顾性分析。所有患者均进行了物理预防。在2009年4月之前,当D - 二聚体值未按预期下降、创伤和手术后5天超过20μg/mL或在下降一段时间后升高至20μg/mL以上时,通过增强计算机断层扫描或超声进行VTE筛查。2009年4月之后,无论D - 二聚体值如何,均在术前和术后常规进行超声检查。根据是否存在伴随损伤将患者分为两组,伴随损伤包括头部、胸部、腹部或脊柱损伤以及骨盆和下肢的其他骨折。总体而言,分别在28例(25.7%)患者和5例(4.6%)患者中检测到VTE和肺血栓栓塞。所有病例均无症状。孤立骨折患者的VTE发生率在旧筛查方法时为8.6%,新筛查方法时为40%;有伴随损伤患者的VTE发生率在旧筛查方法时为25%,新筛查方法时为41.7%。孤立骨折患者的肺血栓栓塞发生率在旧筛查方法时为2.9%,新筛查方法时为0%;有伴随损伤患者的肺血栓栓塞发生率在旧筛查方法时为3.2%,新筛查方法时为25.0%。外科医生应对下肢远端骨折患者的VTE症状保持警惕。