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[断奶后多系统消耗综合征(PMWS)动物疫病流行末期瑞士养猪场中与感染相关的繁殖障碍]

[Infection related fertility disorders in Swiss pig breeding farms at the end of the postweaning multisystemic wasting syndrome (PMWS) epizooty].

作者信息

Handke M, Engels M, Prohaska S, Keller Ch, Brugnera E, Sydler T, Sidler X

机构信息

Departement für Nutztiere, Abteilung Schweinemedizin, Universität Zürich.

出版信息

Schweiz Arch Tierheilkd. 2012 Oct;154(10):437-44. doi: 10.1024/0036-7281/a000380.

Abstract

Porcine Circovirus type 2 (PCV2) is able to induce reproductive failures. 286 fetuses from 113 sows of 59 farms with increased reproductive disorders which included abortions, mummies, stillborn and weak born piglets were studied six years after the beginning of the epizooty of postweaning multisystemic wasting syndrome (PMWS) in Switzerland. 14 % of the cases were bacterial infections based on histological signs of inflammation and pathogen isolation. 12 % further cases showed inflammatory reactions by histology without pathogen identification. PCV2 was identified in only 4 % of cases by immunohistochemistry (IHC). Thus, PCV2 infections are of minor importance in respect to pig reproductive failures in Switzerland. Porcine parvovirus (PPV) infections were found in 3 % of the cases and seem to occur more infrequently compared to former findings. Hitherto, Enteroviruses/Teschovirus were marginally studied in etiologically undefined cases with a prevalence of 11 %. To our knowledge this is the first identification of Enteroviruses/Teschovirus in fetal tissue from reproductive failures in Switzerland. The etiology remained unclear in more than 50 % of all cases in spite of modern diagnostic methods.

摘要

猪圆环病毒2型(PCV2)能够引发繁殖障碍。在瑞士断奶后多系统消耗综合征(PMWS) epizooty开始六年后,对来自59个农场的113头母猪的286头胎儿进行了研究,这些农场的繁殖障碍有所增加,包括流产、木乃伊化、死产和弱仔。根据炎症的组织学迹象和病原体分离,14%的病例为细菌感染。另外12%的病例通过组织学显示有炎症反应,但未鉴定出病原体。通过免疫组织化学(IHC)仅在4%的病例中鉴定出PCV2。因此,在瑞士,PCV2感染对猪繁殖障碍的影响较小。在3%的病例中发现了猪细小病毒(PPV)感染,与以前的发现相比,似乎发生得更不频繁。迄今为止,在病因不明的病例中,肠道病毒/特斯病毒的研究很少,患病率为11%。据我们所知,这是瑞士首次在繁殖障碍的胎儿组织中鉴定出肠道病毒/特斯病毒。尽管采用了现代诊断方法,但超过50%的病例病因仍不清楚。

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