Laboratory of Bioorganic Chemistry and Chemical Biology, Center for Nanotechnology, Heisenbergstraße 11, 48149 Münster, Germany.
J Org Chem. 2012 Oct 19;77(20):9352-6. doi: 10.1021/jo3014319. Epub 2012 Oct 8.
A new, easy-to-prepare and highly selective pyrene-linked tris-triazole amine fluorescent chemosensor has been designed from tripropargylamine and pyrene azide using Cu(I)-catalyzed click chemistry. The fluorescence on-off sensor 1 is highly selective for Zn(2+) displaying a ratiometric change in emission. The relative intensity ratio of monomer to excimer fluorescence (M(376)/E(465)) of the sensor increases 80-fold upon the addition of 10 equiv of Zn(2+) ions (with a detection limit of 0.2 μM).
一种新型的、易于制备且对三唑胺荧光化学传感器具有高选择性的三联三嗪胺荧光化学传感器，是由三丙炔胺和叠氮基芘通过铜（I）催化的点击化学合成的。荧光开关传感器 1 对 Zn(2+)具有高度选择性，表现出发射的比率变化。当加入 10 当量的 Zn(2+)离子时，传感器的单体到激基缔合物荧光（M(376)/E(465)）相对强度比增加了 80 倍（检测限为 0.2 μM）。
