Yoneda S, Senda K, Hayashi K
Jpn Circ J. 1979 Nov;43(11):1048-54. doi: 10.1253/jcj.43.1048.
In this present paper, the authors would like to present here two points of results from the experimental study concerning virus myocarditis in culture. One is the direct delicate features of heart cells affected with Coxsackie B3 (Cox. B3) virus viewed through both light microscope and electron microscope. The other is the fact that marked proliferation of fibroblastic cells take place to replace the heart cells impaired by the virus suggesting to us the possibility of one of the genesisses, revealing fibroblastic involvement in the Idiopathic Cardiomyopathy (ICM) which could be followed by the residual of the virus myocarditis.
在本论文中，作者希望在此展示关于培养中的病毒性心肌炎实验研究的两点结果。其一为通过光学显微镜和电子显微镜观察到的受柯萨奇B3（Cox. B3）病毒感染的心脏细胞的直接精细特征。其二是成纤维细胞显著增殖以取代被病毒损伤的心脏细胞这一事实，这向我们暗示了发病机制之一的可能性，揭示了成纤维细胞参与特发性心肌病（ICM），而这可能继发于病毒性心肌炎的残留情况。
