Roncada Eduardo Vinicius Mendes, Abreu Marilda Aparecida Milanez Morgado de, Pereira Mayra Falcão, Oliveira Claúdia Cardoso Macedo de, Nai Gisele Alborghetti, Soares Deusita Fernandes Gandia
Dermatology Service, Regional Hospital of Presidente Prudente, University of the West Paulista Region, São Paulo, Brazil.
An Bras Dermatol. 2012 Sep-Oct;87(5):752-5. doi: 10.1590/s0365-05962012000500014.
Calciphylaxis, also known as calcific uremic arteriolopathy, is a severe complication often observed in patients with hyperparathyroidism secondary to chronic renal failure, which occurs mainly in women. It is characterized by ischemic tissue loss secondary to progressive vascular compromise. This is a rare and severe condition and its pathogenesis is unclear. The best treatment is prevention, especially in order to maintain adequate levels of calcium and phosphorus. We describe a case of this disease in a patient with hyperparathyroidism secondary to chronic renal failure who underwent medical treatment, surgical debridement and total skin autografts, with resolution of symptoms after 6 months.
钙过敏症，也称为钙化性尿毒症性小动脉病，是一种常见于继发于慢性肾衰竭的甲状旁腺功能亢进患者的严重并发症，主要发生在女性身上。其特征是由于进行性血管损害导致缺血性组织损伤。这是一种罕见且严重的病症，其发病机制尚不清楚。最佳治疗方法是预防，尤其是要维持钙和磷的适当水平。我们描述了一例继发于慢性肾衰竭的甲状旁腺功能亢进患者的该疾病病例，该患者接受了药物治疗、手术清创和全厚自体皮肤移植，6个月后症状得到缓解。
