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脊柱侧凸相关躯干畸形的非侵入性临床评估。

Non invasive clinical assessment of trunk deformities associated with scoliosis.

出版信息

IEEE J Biomed Health Inform. 2013 Mar;17(2):392-401. doi: 10.1109/TITB.2012.2222425. Epub 2012 Oct 3.

DOI:10.1109/TITB.2012.2222425
PMID:23047883
Abstract

Besides the spinal deformity, scoliosis modifies notably the general appearance of the trunk resulting in trunk rotation, imbalance and asymmetries which constitutes patients' major concern. Existing classifications of scoliosis, based on the type of spinal curve as depicted on radiographs, are currently used to guide treatment strategies. Unfortunately, even though a perfect correction of the spinal curve is achieved, some trunk deformities remain, making patients dissatisfied with the treatment received. The purpose of this study is to identify possible shape patterns of trunk surface deformity associated with scoliosis. First, trunk surface is represented by a multivariate functional trunk shape descriptor based on 3D clinical measurements computed on cross sections of the trunk. Then, the classical formulation of hierarchical clustering is adapted to the case of multivariate functional data and applied to a set of 236 trunk surface 3D reconstructions. The highest internal validity is obtained when considering 11 clusters that explain up to 65% of the variance in our dataset. Our clustering result shows a concordance with the radiographic classification of spinal curves in 68% of the cases. As opposed to radiographic evaluation, the trunk descriptor is three-dimensional and its functional nature offers a compact and elegant description of not only the type, but also the severity and extent of the trunk surface deformity along the trunk length. In future work, new management strategies based on the resulting trunk shape patterns could be thought of in order to improve the esthetic outcome after treatment, and thus patients satisfaction.

摘要

除了脊柱畸形外,脊柱侧凸还显著改变了躯干的整体外观,导致躯干旋转、不平衡和不对称,这是患者最关心的问题。目前使用的脊柱侧凸分类方法是基于 X 光片上显示的脊柱曲线类型,用于指导治疗策略。不幸的是,即使脊柱曲线得到了完美的矫正,一些躯干畸形仍然存在,使患者对所接受的治疗不满意。本研究的目的是确定与脊柱侧凸相关的可能的躯干表面畸形的形状模式。首先,通过基于躯干横断面的 3D 临床测量计算的多变量功能躯干形状描述符来表示躯干表面。然后,将层次聚类的经典公式应用于多变量函数数据,并应用于一组 236 个躯干表面 3D 重建。当考虑到 11 个聚类时,获得了最高的内部有效性,这些聚类可以解释我们数据集 65%的方差。我们的聚类结果与脊柱曲线的 X 光分类在 68%的病例中是一致的。与 X 光评估相反,躯干描述符是三维的,其功能性质不仅可以紧凑而优雅地描述躯干表面畸形的类型,还可以描述其严重程度和沿躯干长度的范围。在未来的工作中,可以考虑基于所得到的躯干形状模式的新管理策略,以改善治疗后的美观效果,从而提高患者的满意度。

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Reliability of automated topographic measurements for spine deformity.脊柱畸形的自动地形测量的可靠性。
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